Results 141 to 150 of about 6,733 (210)

Diagnostic and Therapeutic Dilemmas in Recurrent Pulmonary Alveolar Proteinosis After Bilateral Lung Transplantation

Respirology Case Reports, Volume 14, Issue 6, June 2026.
Pulmonary alveolar proteinosis (PAP) is an ultra‐rare lung disease that can recur even years after bilateral lung transplantation, as in this 73‐year‐old man whose diagnosis was delayed by PAS‐negative BAL and overlapping opportunistic infections (Nocardia, MAC, Aspergillus). Despite initially normal post‐transplant spirometry, he developed progressive
Omar Lopez, Deven Gupta, Shreya Podder, Ajay Wagh   +3 more
wiley   +1 more source

Characterising Patient Pathways Prior to the Diagnosis of Interstitial Lung Disease

Respirology, Volume 31, Issue 6, Page 599-609, June 2026.
ABSTRACT Background and Objective Interstitial lung diseases (ILDs) lead to breathlessness, cough, deteriorating quality of life and early death. Patients are typically diagnosed late in their disease course when existing lung damage cannot be reversed.
Caitlin C. Fermoyle, John Townend, Vidya Navaratnam, Nicole Goh, Francesca Gonnelli, Neva Eleangovan, Ursie Smith, Heath Heatley, Victoria Carter, David B. Price, Richard Hubbard, Tamera J. Corte   +11 more
wiley   +1 more source

Early Risk Assessment and Recognition of Allergies in Children: Rationale, Methodology, and Proposed Algorithms

Allergy, Volume 81, Issue 6, Page 1971-1984, June 2026.
ABSTRACT Background Atopic diseases—including atopic dermatitis (AD), food allergy (FA), allergic rhinitis (AR), and asthma—are the most common chronic conditions in childhood and adolescence, affecting up to 30% of the global population. In Germany alone, more than 2.1 million children and adolescents are affected.
E. Hamelmann, B. Schaub, K. Beyer, K. Blümchen, M. Gerstlauer, M. V. Kopp, L. Lange, S. Lau, N. Maison, H. Ott, S. M. Schmidt, T. Spindler, C. Traidl‐Hoffmann, C. Vogelberg   +13 more
wiley   +1 more source

Early Introduction and Other Characteristics in Children With Suspected Severe Peanut or Tree Nut Allergy: Finnish Cohort

Acta Paediatrica, Volume 115, Issue 6, Page 1230-1236, June 2026.
ABSTRACT Aim Peanut and tree nut allergies are leading causes of food‐induced anaphylaxis in children. We aimed to examine early introduction and allergic characteristics in children with suspected severe peanut and/or tree nut allergy. Methods Children aged 3–16 years with suspected severe peanut and/or tree nut allergy were recruited from Tampere ...
Emilja Särkkä, Lasse Saarimäki, Jennifer L. P. Protudjer, Iida Ojaniemi, Jussi Karjalainen, Heini Huhtala, Sandra Ekström, Inger Kull, Juho E. Kivistö   +8 more
wiley   +1 more source

Safety, tolerability, pharmacokinetics and pharmacodynamics of the spleen tyrosine kinase inhibitor BI 894416 in healthy volunteers and patients with asthma

British Journal of Pharmacology, Volume 183, Issue 11, Page 2660-2674, June 2026.
Abstract Background and Purpose Spleen tyrosine kinase (SYK) has broad biological functions in inflammation and immunity. The orally administered SYK inhibitor BI 894416 was investigated in a single‐rising‐dose Phase I study in healthy volunteers and in a combined single‐ and multiple‐rising‐dose Phase Ib study in patients with mild asthma ...
Saskia Carstensen‐Aurèche, Tobias Litzenburger, Dorothy De Sousa, Reinhard Sailer, Ewald Benediktus, Denis Delic, Fabian Müller, Meike Müller, Jens M. Hohlfeld   +8 more
wiley   +1 more source

Editorial: Pharmacology Education Special Issue

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Jennifer A. Koenig, Steven J. Tucker
wiley   +1 more source

Respiratory Biomarkers: An Opportunity for Patient‐Centric Microsampling Approach for Treatment Optimization

Clinical and Translational Science, Volume 19, Issue 6, June 2026.
Overview of patient centric microsampling approach for monitoring respiratory biomarkers for treatment optimization. Image created in BioRender. Khan, A. (2026) https://BioRender.com/17jm5cs. ABSTRACT The clinical heterogeneity of respiratory disorders emphasizes the need for personalized approaches to prevention, diagnosis, and therapy.
Ahmar Khan, Jacqueline L. Stair, Daniel Baker, Neil Spooner, Darragh Murnane   +4 more
wiley   +1 more source

Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID

Immunology, Volume 178, Issue 2, Page 261-268, June 2026.
The complement cascade, a series of blood proteins that assists in the recognition and neutralisation of pathogens, either independently or in conjunction with antibodies, is persistently activated in patients with long COVID. We found that blood plasma samples from patients with long COVID contained elevated concentrations of the mannan‐binding lectin‐
Samuel B. K. Keat, Priyanka Khatri, Youssif M. Ali, Chanuka H. Arachchilage, Gregory Demopulos, Kirsten Baillie, Kelly L. Miners, Kristin Ladell, Samantha A. Jones, Helen E. Davies, David A. Price, Wioleta M. Zelek, B. Paul Morgan, Wilhelm J. Schwaeble, Nicholas J. Lynch   +14 more
wiley   +1 more source

The Impact of Airway Oxidative Stress on Macrophage Polarization in Stable Asthma and COPD: Association With Clinical Features in a Prospective Observational Study

Journal of Cellular and Molecular Medicine, Volume 30, Issue 11, June 2026.
ABSTRACT The polarization status of pulmonary macrophages is dependent on cytokines and mediators present locally in the airways. This study aimed to evaluate whether oxidative stress present in the airways of asthma or COPD patients promotes M1 or M2 macrophage polarization.
Magdalena Paplińska‐Goryca, Małgorzata Proboszcz, Monika Wróbel, Magdalena Radziszewska, Katarzyna Mycroft‐Rzeszotarska, Rafał Krenke   +5 more
wiley   +1 more source

[Spirometry].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1992
K, Andersen, G A, Rosland
openaire   +1 more source