Results 111 to 120 of about 38,796 (219)

First‐In‐Human Safety, Pharmacokinetics, and Pharmacodynamics of VENT‐02 Freebase, a CNS‐Penetrant NLRP3 Inhibitor

open access: yesClinical and Translational Science, Volume 19, Issue 5, May 2026.
ABSTRACT The NLRP3 inflammasome is a central mediator of innate immunity and a key driver of inflammatory and neurodegenerative diseases. VENT‐02 is orally bioavailable, central nervous system‐penetrant, selective small‐molecule inhibitor of NLRP3. This first‐in‐human, randomized, double‐blind, placebo‐controlled study assessed the safety, tolerability,
Lisanne C. A. Smidt   +14 more
wiley   +1 more source

Regulation of Endoplasmic Reticulum Stress by Empagliflozin in Doxorubicin‐Induced Cardiotoxicity in Rats

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Although Doxorubicin (Dox) is an effective anticancer drug, it can cause severe cardiotoxicity. While several mechanisms have been proposed to explain Dox‐induced cardiomyopathy (DIC), strategies to prevent it remain limited. In previous research on isolated cardiomyocytes, we identified that Empagliflozin (EMPA), an antidiabetic drug ...
Akshi Malik   +6 more
wiley   +1 more source

Tag der Bibliotheken in Berlin & Brandenburg 2017

open access: yeso-bib. Das offene Bibliotheksjournal, 2017
Indra Heinrich
doaj   +1 more source

AHP UNTUK PEMODELAN SPK PEMILIHANSEKOLAH TINGGI KOMPUTER

open access: yesRespati, 2017
dalam pengambilan keputusan untuk permasalahan semi terstruktur dengan tujuan sebagai alat bantu bagi para manajer untuk memperluas kapabilitas mereka dalam pengambilan keputusan dan bukan untuk menggantikan manajer. Pengambilan keputusan pada dasarnya adalah sebuah pemilihan dari beberapa alternatif pilihan dengan  harapan akan menghasilkan  sebuah ...
Yuli Astuti, M. Suyanto, Kusrini Kusrini
openaire   +2 more sources

SPK-Connect

open access: yes, 2018
El objetivo de este trabajo de fin de carrera es la realización de un prototipo que permita dar información complementaria sobre el estado de una máquina de enfardado industrial. Junto con la empresa CONTROLPACK.SL, líder en el sector del “packaging”, se pretende realizar el proyecto SPK-Connect, un proyecto basado en la industria 4.0 que pretende ...
openaire   +1 more source

Incidence, severity and factors related to drug-induced keratoepitheliopathy with glaucoma medications

open access: yesClinical Ophthalmology, 2010
Takeo Fukuchi, Kimiko Wakai, Kieko Suda, Tomoko Nakatsue, Hideko Sawada, Hiroaki Hara, Jun Ueda, Takayuki Tanaka, Akiko Yamada, Haruki AbeDivision of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University ...
Takeo Fukuchi   +3 more
doaj  

Impact of simultaneous pancreas-kidney transplantation: patients' perspectives

open access: yesPatient Preference and Adherence, 2012
P Isla Pera,1 J Moncho Vasallo,2 O Guasch Andreu,3 MJ Ricart Brulles,4 A Torras Rabasa4,51Public Health Department, Nursing School, Universitat de Barcelona, Barcelona, 2Community Nursing, Preventive Medicine and Public Health and History of Science ...
Isla Pera P   +4 more
doaj  

Distal transplant pancreatectomy during SPK: successful clinical outcome.

open access: yesInternational surgery, 2008
Simultaneous pancreas and kidney transplantation (SPK) is considered an extremely effective and well-established therapeutic option for selected patients with end-stage renal disease (ESRD), secondary to type 1 diabetes. Vascular complications in pancreas transplantation are more common than in any other solid organ transplant.
Vlachos, K.   +4 more
openaire   +2 more sources

Spk/Oecd Semineri

open access: yesİktisat İşletme ve Finans, 1989
Jamshed GHANDHİ   +5 more
openaire   +1 more source

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