Results 31 to 40 of about 4,648 (196)

Immune Checkpoint Inhibitor as a Fifth Component of Lipid Nanoparticles Enables Lymph Node‐Targeting and Augments mRNA Vaccine Efficacy

open access: yesAdvanced Science, EarlyView.
Here, a PDL1 inhibitor is employed as a fifth component to modify lipid nanoparticles (LNPs). PDL1 inhibitor‐loaded LNPs show enhanced lymph node targeting, resulting in greater lymph node expansion, immune cell infiltration, and improved mRNA vaccine efficacy. This fifth component LNP could be a novel platform for mRNA vaccines.
Minki Ha   +5 more
wiley   +1 more source

MENENTUKAN PEMENANG KONVENSI QUALITY IMPROVEMENT CIRCLE DENGAN METODE WEIGHTED PRODUCT DAN SIMPLE ADDITIVE WEIGHTING

open access: yesIlkom Jurnal Ilmiah, 2018
Pengambilan keputusan untuk menentukan pemenang dalam suatu konvensi atau kompetisi merupakan suatu hal yang cukup sulit dilakukan secara konvensional. Kesulitan akan semakin terasa dengan bertambahnya alternatif dan kriteria yang dimasukkan.
Deni Kurniawan   +2 more
doaj   +1 more source

Implementasi Metode Simple Multi Attributerating Technique (SMART) dalam Keputusan Pemilihan Model Pembelajaran di Masa Pandemi Covid-19

open access: yesTechno.Com, 2021
Penelitian ini bertujuan memilih model pembelajaran yang tepat pada masa pandemi Covid-19. Covid-19 menyebabkan seluruh aktivitas dilakukan dari rumah. Selama ini kegiatan pembelajaran dilakukan secara tatap muka manajemen Politeknik tempat penulis dan ...
Jakariya Sembiring   +2 more
doaj   +1 more source

Long‐Term Human Skin Platform for Modeling Chronic Inflammation, Environmental Stress, and Therapeutic Intervention

open access: yesAdvanced Science, EarlyView.
An advanced, long‐term human skin platform maintains native skin structure and key tissue functions for up to four weeks. The platform models chronic inflammation, aging‐related skin changes, and UVB damage, enabling drug and topical interventions—including anti‐inflammatory therapy, senolytic treatment, and sunscreen—to be evaluated in intact human ...
Purnendu Kumar Sharma   +14 more
wiley   +1 more source

PReS13-SPK-1588: Recurrent fevers [PDF]

open access: yesPediatric Rheumatology, 2013
Fevers are common in childhood, usually due to infections. Some children however experience recurrent episodes of seemingly unprovoked fevers. These so-called periodic fever syndromes are rare diseases. Clinically they are characterized by generalized inflammation and different combinations of localized tissue inflammation. Skin and joints are often
openaire   +1 more source

Molecular Electrocatalysis Coupled With a Palladium Membrane Reactor Affords Selective Nitrogen Reduction

open access: yesAdvanced Science, EarlyView.
A palladium membrane reactor delivers active hydrogen to homogeneous nickel terpyridine catalysts, which then selectively hydrogenate dinitrogen to ammonia. ABSTRACT Ammonia production is a cornerstone of modern industry and society, yet the conventional Haber–Bosch process accounts for nearly 2% of the global CO2 emissions. A promising and potentially
Morgan McKee   +11 more
wiley   +1 more source

Ecoefficiency Analysis and Regression in Data Conversion for Spiking Neural Network Training

open access: yesAdvanced Intelligent Systems, EarlyView.
The environmental footprint of spiking neural networks is quantified during dataset encoding and training for autonomous driving regression across three benchmarks. Temporal depth emerges as the dominant driver of energy consumption and CO2 emissions, while the accuracy–energy trade‐off proves dataset‐dependent. On conventional hardware, spiking models
Fernando S. Martínez   +3 more
wiley   +1 more source

Grenzflächen‐Synergie zwischen Mn und Kohlenstoffnitrid ermöglicht die selektive photokatalytische C–H‐Chlorierung mittels Einzelatomkatalyse

open access: yesAngewandte Chemie, EarlyView.
Ein Mangan‐Einzelatom‐Photokatalysator auf funktionalisiertem Kohlenstoffnitrid ermöglicht die selektive, durch sichtbares Licht angetriebene C(sp2)–H‐Chlorierung. DFT‐gestützte mechanistische Untersuchungen zeigen, dass die photoinduzierte Ladungstrennung NCS aktiviert, während isolierte Mn‐Zentren Mn–Cl‐Intermediate an der Katalysatorgrenzfläche ...
Jaro Vanderghinste   +16 more
wiley   +1 more source

Sistem Pendukung Keputusan Penentuan Lokasi Embung dengan Menggunakan Metode Višekriterijumsko Kompromisno Rangiranje (VIKOR)

open access: yesJUTEI (Jurnal Terapan Teknologi Informasi), 2023
Kekeringan merupakan salah satu permasalahan lingkungan hidup yang secara spesifik akan menimbulkan permasalahan yang serius bila terjadi dalam waktu yang berkepanjangan.
Akhmad Ali Sajidin   +2 more
doaj   +1 more source

PReS13-SPK-1469: Juvenile scleroderma [PDF]

open access: yesPediatric Rheumatology, 2013
Juvenile localized scleroderma, also known as morphea, is the more frequent subtype of scleroderma in childhood. It comprises a group of distinct conditions which involve the skin and subcutaneous tissues. They range from very small plaques of fibrosis involving only the skin, to diseases which may cause significant functional and cosmetic deformity.
openaire   +1 more source

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