Results 21 to 30 of about 39,159 (206)

Successful Splenectomy for Hypersplenism in Wilson's Disease: A Single Center Experience from China.

open access: yesPLoS ONE, 2015
Splenomegaly and pancytopenia are common in Wilson's disease (WD) and splenectomy is one of the conventional treatments for splenomegaly and the associated pancytopenia.
Liang-Yong Li   +8 more
doaj   +1 more source

OUTCOME OF SPLENECTOMY IN THE TREATMENT OF ITP – ONE CENTER EXPERIENCE

open access: yesHematology, Transfusion and Cell Therapy, 2021
Objective: Immune thrombocytopenia (ITP) is a disease with variable clinical presentation, requiring different treatment lines. Splenectomy is used as a second- or third-line therapy for ITP.
Weronika Lebowa   +2 more
doaj   +1 more source

The risks and benefits of non-predictive splenectomy: The necessity of splenectomy and early postoperative outcomes

open access: yesMedicine Science, 2019
Although, most splenectomy is predictive due to preoperative tests, sometimes the decision to perform the splenectomy is made intraoperatively for non-primary splenic diseases. The aim of this study to investigate the risks, benefits and necessity of non-
Yusuf Gunay, Ilhan Tasdoven
doaj   +1 more source

History of splenectomy

open access: yesInternational Journal of Surgery, 2013
The spleen has been considered for millennia a fascinating and mysterious organ with multiple functions. The spleen has long been an organ of interest in popular as well as medical literature.A literature (Pubmed) and historical review about splenectomy has been performed.The importance of spleen and the related surgical procedure of splenectomy has ...
DIONIGI, RENZO   +4 more
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

open access: yesAdvanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian   +13 more
wiley   +1 more source

Redefining the Role of Splenectomy in Scirrhous Gastric Cancer: Toward a Selective Multimodal Strategy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Scirrhous gastric cancer, characterized by diffuse infiltration and a high propensity for peritoneal dissemination, remains one of the most aggressive subtypes of gastric cancer. Despite a relatively high incidence of splenic hilar lymph node (No. 10) metastasis, the oncologic benefit of splenectomy remains controversial, while its association
Tsutomu Hayashi, Takaki Yoshikawa
wiley   +1 more source

Evaluation of Refractory Autoimmune Hemolytic Anemia Patients After Splenectomy

open access: yesCerrahpaşa Medical Journal
Objective: In this study, we aimed to retrospectively evaluate the results of patients with autoimmune hemolytic anemia (AIHA) who had undergone splenectomy.
Mehmet Günhan Tekin, Memiş Hilmi Atay
doaj   +1 more source

Risk of pneumonia among patients with splenectomy: a retrospective population-based cohort study

open access: yesAnnals of Saudi Medicine, 2017
BACKGROUND: People without a spleen are particularly susceptible to various overwhelming infections including pneumonia. Although the association between splenectomy and pneumonia has been previously studied, there has been no study using the national ...
Shih-Wei Lai, Cheng-Li Lin, Kuan-Fu Liao
doaj   +1 more source

Splenectomy does not improve survival in chronic active Epstein-Barr virus disease patients

open access: yesAnnals of Hematology
We aimed to evaluate the clinical value of splenectomy as a treatment for Chronic active Epstein-Barr virus disease (CAEBVD). We retrospectively reviewed the clinical data from clinical records of patients received splenectomy in our institution from ...
Junzhe Wang   +7 more
doaj   +1 more source

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