Results 51 to 60 of about 39,159 (206)

Thrombocytosis and the generation of platelet‐derived microparticles in the pathophysiology of sickle cell disease

British Journal of Haematology, EarlyView.
Thrombocytosis is associated with an increased production of platelet‐derived microparticles from activated platelets, which contribute to vaso‐occlusion in sickle cell disease by perpetuating the cycle of inflammation, procoagulant state and endothelial dysfunction.
Giao N. Lê, Anna Dillon, Owen P. Smith, Corrina McMahon   +3 more
wiley   +1 more source

Retrospective Evaluation of the Outcomes of Splenectomy in Patients with β-Thalassemia: Insights from a Tertiary Care Center in Bahawalpur

Life and Science
Objective: To evaluate outcomes of splenectomy in patients with β-thalassemia major. Study Design: A retrospective study. Place and Duration of Study: The study was conducted at the Department of Hematology, Bahawal Victoria Hospital Bahawalpur ...
Muhammad Irfan khan, Faseeh Abid, Hafsa Malik, Nadeem Shahid Younas, Ayesha Sarfaraz, Nausherwan Malik, Haris Irfan Khan   +6 more
doaj   +1 more source

Hemoglobin Lepore‐Boston‐Washington: A Rare Cause of Unmeasurable HbA1c and Diagnostic Challenge in Diabetes

Journal of Clinical Laboratory Analysis, EarlyView.
Filippo Russo, Silvia Trombetti, Maria Rosaria Storino, Raffaele Sessa, Carmela De Felice, Giuseppe Schiavone, Michela Grosso   +6 more
wiley   +1 more source

Splenectomy Impact and Outcome Among Patients With Sickle Cell Disease: A Cross‐Sectional Study

Health Science Reports
Background It is common to perform a splenectomy for patients with sickle cell disease (SCD); however, our understanding of its impact on long‐term clinical outcomes remains incomplete.
Mortadah Alsalman, Zainab Bu‐Khamsin, Fatimah AlSahaf, Fatima Al Amer, Fatema Alhelal, Ali Essa, Mohammed Alessa, Somaia Shehab‐Eldeen, Abdallah Essa   +8 more
doaj   +1 more source

RITUXIMAB VERSUS SPLENECTOMY IN CHRONIC PRIMARY ITP: EXPERIENCE OF A SINGLE HEMATOLOGY CLINIC

Mediterranean Journal of Hematology and Infectious Diseases
Objective: Immune thrombocytopenia (ITP) is an acquired immune-mediated disease that lacks an underlying etiology. Steroids are the main first-line treatment of ITP, while the second-line treatment consists primarily of splenectomy and rituximab.
Rawanda Shamoon, Ahmed Khudair Yassin, Sarah Laith Alnuaimi   +2 more
doaj   +1 more source

Survival outcomes and treatment patterns in myelofibrosis in the JAK inhibitor era

British Journal of Haematology, EarlyView.
Summary Data on real‐world survival and treatment patterns in large, unselected myelofibrosis (MF) cohorts remain limited. We analysed 1649 patients with MF diagnosed from 2010 onwards and included in the Spanish Myelofibrosis Registry across 64 centres. Janus kinase (JAK) inhibitors were administered to approximately half of the patients.
Juan‐Carlos Hernández‐Boluda, Eduardo Arellano‐Rodrigo, Manuel Pérez‐Encinas, José‐María Raya, María‐Teresa Gómez‐Casares, Francisca Ferrer‐Marín, Alberto Hernández‐Sánchez, María‐Laura Fox, Anna Angona, Beatriz Cuevas, María‐Isabel Mata‐Vázquez, Rosa Ayala, Natalia de las Heras, Elvira Mora, Valentín García‐Gutiérrez, Alicia Senín, Jasson Villarreal, Blanca Xicoy, Raúl Pérez‐López, María García‐Fortes, Sonia González de Villambrosia, Elena Magro, María‐José Ramírez, Paula Gómez, Angel Ramírez‐Payer, Clara Martínez‐Valverde, Lucía Pérez‐Lamas, Carmen García‐Hernández, Mercedes Gasior, Luis‐Miguel Juárez‐Salcedo, Francisco Ibáñez, María‐Luisa Antelo, Lucía Guerrero, Alberto Alvarez‐Larrán, Arturo Pereira, on behalf of the Spanish MPN Group (GEMFIN)   +35 more
wiley   +1 more source

Identification of predictive factors for reversal of cerebral vasculopathy in an original longitudinal cohort study in newborns with sickle cell anaemia

British Journal of Haematology, EarlyView.
Summary Cerebral macrovasculopathy (CV) is a major complication in children with sickle cell anaemia (SCA) and usually requires a long‐term transfusion programme (TP) to prevent stroke. This study aimed to identify factors predicting reversal of CV on TP in a single‐centre newborn cohort. Among 375 patients, 50 presented CV and received TP.
Julie Sommet, Priscilla Boizeau, Zinedine Haouari, Berengère Koehl, Monique Elmaleh, Emmanuelle Lesprit, Florence Missud, Ghislaine Ithier, Laurent Holvoet, Valentine Brousse, Christophe Delclaux, André Denjean, Suzanne Verlhac, Corinne Alberti, André Baruchel, Nathalie Couque, Malika Benkerrou   +16 more
wiley   +1 more source

Splenectomy Does Not Increase COVID-19 Risk or Mortality in Abdominal Cancer Surgery: A Retrospective Cohort Analysis

Cerrahpaşa Medical Journal
Objective: Splenectomy is frequently performed in abdominal malignancy surgeries due to direct tumor invasion, vascular injury, or for technical reasons.
Rıza Deryol, Gökhan Avşar, Musluh Hakseven, Serdar Çulcu, Güngör Utkan, Ali Ekrem Ünal   +5 more
doaj   +1 more source

Pneumococcal and influenza immunization in asplenic persons: a retrospective population-based cohort study 1990-2002

BMC Infectious Diseases, 2010
Background Splenectomy is associated with increased risk for bacteremia, due to impaired clearance of bloodborne agents and to altered phagocytosis and humoral immunity.
Dodds Linda, Langley Joanne M, Fell Deshayne, Langley G Ross   +3 more
doaj   +1 more source

Five Advances in Benign Pancreatic Surgery in the Last 50 Years

World Journal of Surgery, EarlyView.
Stephan B. Dreyer, Rowan W. Parks
wiley   +1 more source