Results 191 to 200 of about 132,470 (303)

B-Mode Ultrasonographic Evaluation and Reference Dimensions of the Liver and Spleen in Healthy Lactating Saanen Goats. [PDF]

Vet Radiol Ultrasound
Silva TVD, Moreira IB, Carvalho RDS, Santiago CBA, Balaro MFA.   +4 more
europepmc   +1 more source

NUDT21 Drives T‐Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

Advanced Science, EarlyView.
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu, Jianwei Wang, Zhiheng Li, Qi Ji, Hui Zhang, Qinyi Zhang, Senlin Zhang, Juanjuan Yu, Yanfang Tao, Yijun Wu, Chunxia Shi, Zong Zai, Zimu Zhang, Yizhen Li, Zhenjiang Bai, Shaoyan Hu, Jian Pan, Yang Yang, Shuiyan Wu   +18 more
wiley   +1 more source

Splenic abscess caused by Porphyromonas gingivalis septicemia: a case report. [PDF]

BMC Infect Dis
Wang C, Lou T.
europepmc   +1 more source

Endogenous Ceramide 24:1 Constrains Th17‐Driven Neutrophilic Inflammation by Antagonizing EP2 Signaling

Advanced Science, EarlyView.
Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu, Abudureyimujiang Aili, Zheng Kuang, Liting Cao, Zemin Li, Ying Shang, Yingying Ge, Tingting Hu, Yongchang Sun, Wuli Zhao, Rong Jin, Chun Chang   +11 more
wiley   +1 more source

Gaucher's Disease Verified by Splenic Puncture [PDF]

Proceedings of the Royal Society of Medicine, 1931
openaire   +2 more sources

Left-Sided Portal Hypertension Induced by Splenic Arteriovenous Malformation: A Case Report. [PDF]

Am J Case Rep
Zhang S, Li H, Cao G, Mei Y, Huang Y, Zhang M.   +5 more
europepmc   +1 more source

An Implanted Tooth That Can Feel

Advanced Science, EarlyView.
To endow the implanted tooth with masticatory perception, herein we demonstrate that a 3D‐printed piezoelectric‐core/robust‐sheath implanted tooth can rebuild the sensing feedback, serving as “mechanoreceptors” in converting the mechanical chewing force to electrical signals, and up to brain through surrounding alveolar nerve system.
Yaru Cao, Zhenhua Wu, Jiwei Sun, Ke Song, Jiayi Li, Yujin Li, Wenqi Chen, Hanyu Li, Shue Li, Cheng Yang, Silin Liu, Yunyun Han, Bin Su, Yumei Ding   +13 more
wiley   +1 more source

Splenic accumulation of intact Plasmodium ovale sensu lato-infected red blood cells in a patient presenting with splenic rupture. [PDF]

PLoS Negl Trop Dis
Benabdelmoumen G, Itani O, Joste V, Houzé S, Hardy D, Bavozet F, Sylla M, Kho S, Anstey NM, Consigny PH, Sissoko A, Buffet P.   +11 more
europepmc   +1 more source

The ITGB2‐COPS3‐SOX2 Axis and SOX2 Liquid‐Liquid Phase Separation: Dual Mechanisms Governing Osteosarcoma Stemness

Advanced Science, EarlyView.
Osteosarcoma stemness is driven by the ITGB2‐COPS3‐SOX2 signaling axis. This study reveals that nuclear COPS3 stabilizes SOX2, which in turn undergoes liquid‐liquid phase separation to promote stemness. Based on this mechanism, a novel COPS3 inhibitor, Z‐5891, was developed, effectively suppressing tumor growth and stemness in vivo, offering a ...
Lei Guo, Zhiqing Zhao, Wei Wang, Jianfang Niu, Bing Wang, Yunfei Lin, Wei Guo, Taiqiang Yan   +7 more
wiley   +1 more source

Chronic Malaria Is Associated With Trauma-related Splenic Rupture Requiring Splenectomy. [PDF]

J Infect Dis
Shanti PAI, Alexander K, Candrawati F, Andries B, Kambuaya NN, Rini H, Amelia AR, Puspitasari AM, Amalia R, Rahmayenti DA, Leonardo L, Prayoga P, Trianty L, Pava Z, Kenangalem E, Auburn S, Price RN, Laksanawati IS, Buffet PA, Noviyanti R, Anstey NM, Poespoprodjo JR, Kho S.   +22 more
europepmc   +1 more source