Results 131 to 140 of about 15,855 (221)

Human erythroid models of sickle cell disease

open access: yesHemaSphere, Volume 10, Issue 10, October 2026.
Abstract Sickle cell disease (SCD) is a group of severe inherited red blood cell disorders causing a major global healthcare burden. Despite recent advances in gene therapy and stem cell transplantation, treatment options remain very limited, highlighting the urgent need for the development of new therapeutic approaches.
Deborah E. Daniels   +5 more
wiley   +1 more source

EHA Guidelines on the management of children and adults with hemoglobin SC disease

open access: yesHemaSphere, Volume 10, Issue 10, October 2026.
Abstract HbSC disease is the second most common type of sickle cell disease (SCD) in populations of African origin. Although it is often grouped together with other types of SCD, particularly sickle cell anemia (HbSS), it has unique pathophysiology and a different spectrum of laboratory and clinical features.
David C. Rees   +15 more
wiley   +1 more source

Diagnostic Accuracy of Shear Wave Elastography for the Assessment of Congestive Liver Disease in Patients With Structural Heart Disease

open access: yesJournal of Clinical Ultrasound, Volume 54, Issue 8, Page 1867-1875, October 2026.
Shear wave elastography demonstrated moderate diagnostic accuracy for detecting congestive liver disease in patients with structural heart disease. Increased liver stiffness was associated with echocardiographic markers of venous congestion, supporting the concept that elastography may serve as a noninvasive marker of cardiohepatic interaction ...
Edinéia Camargo Dziadzio   +4 more
wiley   +1 more source

Frequency of Human Brucellosis Complications in West Asia: A Systematic Review and Meta‐Analysis

open access: yesMicrobiologyOpen, Volume 15, Issue 5, October 2026.
In 51.66% of the included studies in West Asia, the sample size was inadequate for at least half of the complications measured. ABSTRACT Background Brucellosis is a multi‐systemic zoonotic infection. The West Asia/Middle East region is an important global hotspot for brucellosis.
Aliasghar Fakhri‐Demeshghieh   +11 more
wiley   +1 more source

Extracellular Vesicles: Classification, Biological Functions, Diseases, and Therapeutic Opportunities

open access: yesMedComm, Volume 7, Issue 10, October 2026.
• EV content maintains cellular homeostasis and is involved in several disease onset and progression. • miRNA export in EVs depends on: RNA‐binding proteins recognizing motif sequences and on epitranscriptomic modifications. • The disclosure of delivery mechanisms is crucial for developing personalized EV‐based therapeutic tools. ABSTRACT Extracellular
Sabrina Garbo   +4 more
wiley   +1 more source

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