Results 171 to 180 of about 434,859 (340)

Cancer Cell‐Intrinsic Cholesterol Induces Lipid‐Associated Macrophage Differentiation via SP1 Palmitoylation to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
Cancer cell‐intrinsic cholesterol promotes the S‐palmitoylation of SP1, increasing its nuclear translocation and driving the transcription and secretion of MDK, which in turn facilitates the differentiation of macrophages into a lipid‐associated phenotype.
Shirong Peng, Weilong Lin, Zean Li, Ruilin Zhuang, Shengmeng Peng, Bingheng Li, Bingliang Chen, Yong Luo, Yuan Ou, Wei Zhuang, Tao Du, Kaiwen Li, Hai Huang   +12 more
wiley   +1 more source

Splenic extramedullary hematopoietic proliferation in Philadelphia chromosome-negative myeloproliferative neoplasms: heterogeneous morphology and cytological composition

Modern Pathology, 2012
Sonam Prakash, R. Hoffman, Sharon Barouk, Y. L. Wang, Daniel M. Knowles, A. Orazi   +5 more
semanticscholar   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Infections in patients with hematologic neoplasms and hematopoietic stem cell transplantation: neutropenia, humoral, and splenic defects.

Clinical Infectious Diseases, 2011

semanticscholar   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

A descriptive review of cardiac tumours in dogs and cats [PDF]

, 2017
Adissu, Akkoc, Akkoc, Amati, Andersen, Aupperle, Aupperle, Balli, Benvenuti, Berg, Boddy, Bonagura, Boston, Bracha, Brambilla, Briggs, Bright, Brisson, Brower, Buchanan, Burke, Cagle, Cho, Chun, Crumbaker, Darke, De Rycke, Detweiler, Di Palma, Dunning, Dupuy-Mateos, Edwards, Ehrhart, Fernandez-del Palacio, Fews, Fine, Foale, Gallay, Ghaffari, Gonin-Jmaa, Grieco, Hammer, Hayes, Hayes, Ikede, Jacobowitz, Jakab, Keene, Keene, Kerstetter, Kisseberth, Kolm, Krotje, Lana, Linde, Lombard, MacDonald, MacGregor, Machida, Machida, Machida, Madarame, Mai, Mansfield, Mellanby, Merlo, Mullin, Naude, Ogburn, Owen, Perez, Ployart, Prange, Radi, Rajagopalan, Ramoo, Rancilio, Roberts, Rolla, Sanford, Sato, Schelling, Scollan, Shaw, Simpson, Sisson, Sisson, Speltz, Stafford Johnson, Stern, Szczech, Timian, Vaughan, Vicari, Vicini, Walter, Ware, Waters, Weisse, Wey, Wohlsein, Yamamoto, Yamamoto, Yanagawa   +103 more
core   +1 more source

Epidermoid accessory splenic cyst masquerading as a pancreatic mucinous cystic neoplasm [PDF]

Endoscopy, 2008
F C, Gleeson, M L, Kendrick, S T, Chari, L, Zhang, M J, Levy   +4 more
openaire   +2 more sources

Biodegradable Carbonate Nanogels Loaded with Anti MFAP‐5 siRNA for Anti‐stromal Therapy of Hepatocellular Carcinoma

Advanced Science, EarlyView.
Polycarbonate nanogels enable lipid‐free delivery of anti‐MFAP‐5 siRNA into cancer‐associated fibroblasts (CAF) in hepatocellular carcinoma. In a cirrhotic murine model, this approach silences MFAP‐5, reduces fibroblast activation, and suppresses tumor growth by inhibiting NOTCH/Hes1‐driven angiogenesis. CAF‐targeted MFAP‐5 RNAi and conserved signaling
Paul Schneider, Alexander Fuchs, Michael Fichter, Vanessa Bolduan, Jenny Schunke, Özlem Akilli, Nádia C. Correia, Yannick Ehlers, Christian Czysch, Pia Winterwerber, Eliana Stanganello, Barbara Schrörs, Mustafa Diken, Christoph Eckert, Shusruto Rishik, Andreas Keller, Jörn M. Schattenberg, Stephan Grabbe, Matthias Bros, Lutz Nuhn, Leonard Kaps   +20 more
wiley   +1 more source

PRDM1 expression levels in marginal zone lymphoma and lymphoplasmacytic lymphoma [PDF]

, 2017
Hassan, Anjum, Hussaini, Mohammad, Mirza, Abu-Sayeef, Pfeifer, John, Yeung, Cecilia, Zhu, Xiaopei   +5 more
core   +1 more source

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source