Results 41 to 50 of about 52,061 (305)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A case of primary splenic histiocytic sarcoma with liver metastasis

Asian Journal of Surgery
Yangyun Zhou, Kai Zhang, Chuanwen Yu
exaly   +3 more sources

Lung adenocarcinoma and splenic histiocytic sarcoma in an African pygmy hedgehog (Atelerix albiventris)

Brazilian Journal of Veterinary Pathology, 2023
The African pygmy hedgehog is increasingly being kept as a pet, and studies regarding the primary diseases that affect this species are essential for advancing medicine in these animals.
Isabela Coelho Zanoti, Bethânia Almeida Gouveia, Alessandra Loureiro Morales dos Santos, Fernanda Ramalho Ramos, Claudia Momo   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Primary Angiosarcoma of the Spleen: An Oncological Enigma

Case Reports in Oncological Medicine, 2014
Introduction. Primary splenic angiosarcoma is an extremely unusual neoplasm originating from sinusoidal vascular endothelium. Surgical extirpation is the mainstay of treatment of this highly malignant disease. Case Presentation.
Myoteri Despoina, Dellaportas Dionysios, Ayiomamitis Georgios, Strigklis Konstantinos, Kouroumpas Efstratios, Zizi-Sermpetzoglou Adamantia   +5 more
doaj   +1 more source

Mucinous Cystic Neoplasm of the Pancreas is Not an Aggressive Entity [PDF]

, 2014
Objective: Mucinous cystic neoplasms (MCNs) of the pancreas have often been confused with intraductal papillary mucinous neoplasms. We evaluated the clinicopathologic characteristics, prevalence of cancer, and prognosis of a large series of well ...
Bassi, Claudio, Capelli, Paola, Castillo, Carlos Fernández-del, Crippa, Stefano, Domínguez, Ismael, Falconi, Massimo, Lauwers, Gregory Y., Mino-Kenudson, Mari, Pederzoli, Paolo, Salvia, Roberto, Thayer, Sarah P., Warshaw, Andrew Louis, Zamboni, Giuseppe   +12 more
core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Rare Coincidence of Gastric Cancer and Large Myofibroblastic Tumor of The Spleen

Acta Medica Bulgarica
Although its incidence has been decreasing during the last decades, gastric cancer remains a common disease and a global health problem. Conversely, inflammatory myofibroblastic tumors, especially the splenic ones, are extremely rare neoplasms.
Arabadzhieva E.
doaj   +1 more source

Isolated splenic sarcoidosis: A case report

Anales del Sistema Sanitario de Navarra
Isolated splenic sarcoidosis is a rare entity, but clinicians should consider it in patients with compatible clinical features. Its diagnosis is challenging due to the broad differential diagnosis, which includes hematologic and splenic neoplasms ...
Coro Velasco Gametxogoikoetxea, Irene Fernández De Los Reyes, Fermín Jiménez Bermejo   +2 more
doaj   +1 more source

Paraneoplastic Pemphigus and Bronchiolitis Obliterans in a Patient with Splenic B-cell Lymphoma

Journal of the Formosan Medical Association, 2007
Paraneoplastic pemphigus (PNP), also called paraneoplastic autoimmune multiorgan syndrome, is a rare disorder associated with underlying neoplasia.
Shiou-Han Wang, Chia-Yu Chu, Hsuan-Hsiang Chen, Yih-Leong Chang, Kuan-Yu Chen, Hsien-Ching Chiu   +5 more
doaj   +1 more source