Results 101 to 110 of about 69,111 (289)

A higher JAK2V617F allele burden may be a risk factor for hemorrhagic events in younger patients with polycythemia vera

Hematology
Objectives: Hemorrhagic events are a rare but potentially fatal complication in patients with polycythemia vera (PV).Methods: We analyzed the characteristics of hemorrhagic events in 267 patients with PV.Results: A median follow-up of 4.8 years revealed ...
Chiho Furuya, Yoshinori Hashimoto, Soji Morishita, Yasutaka Fukuda, Tadaaki Inano, Tomonori Ochiai, Shuichi Shirane, Yoko Edahiro, Marito Araki, Miki Ando, Norio Komatsu   +10 more
doaj   +1 more source

Chronic Splenomegaly [PDF]

Proceedings of the Royal Society of Medicine, 1937
G, Slot, G S, Caithness
openaire   +2 more sources

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

British Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

SPLENOMEGALY [PDF]

BMJ, 1913
openaire   +2 more sources

TNF‐α partially modulates the endothelial dysfunction during the acute phase of Trypanosoma cruzi infection

British Journal of Pharmacology, EarlyView.
Background and Purpose Whereas the effects of Trypanosoma cruzi (T. cruzi) infection are well‐characterised in the heart, its impact on the vasculature has received little attention. In this study, we investigated the effects of acute and chronic T. cruzi infection on vascular responsiveness and the underlying mechanisms.
Thales M. H. Dourado, Wanessa M. C. Awata, Gustavo F. Pimenta, Barbara M. Marchetti, Maiara V. Providello, Sérgio De Albuquerque, Carlos R. Tirapelli   +6 more
wiley   +1 more source

Hepatosplenomegaly and Pernicious Anaemia [PDF]

Journal of Clinical and Diagnostic Research, 2014
Turgay Ulas, Emel Yigit Karakas, Cemal Bes, Fatih Borlu, Hakan Buyukhatipoglu   +4 more
doaj   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

Biological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning, Federica Agostini, Camila Caldana, Johannes Hartl, Matthias Heinemann, Markus A. Keller, Jan Lukas Krüsemann, Costanza Lamperti, Carole L. Linster, Steffen N. Lindner, Julia Muenzner, Jens Nielsen, Zoran Nikoloski, Bettina Siebers, Jacky L. Snoep, Hezi Tenenboim, Bas Teusink, Spencer J. Williams, Mirjam M. C. Wamelink, Markus Ralser   +19 more
wiley   +1 more source

Pathological roles of MRP14 in anemia and splenomegaly during experimental visceral leishmaniasis

, 2020
Kanna Ishizuka, Wataru Fujii, Natsuho Azuma, Haruka Mizobuchi, Ayako Morimoto, Chizu Sanjoba, Yoshitsugu Matsumoto, Yasuyuki Goto   +7 more
openalex   +2 more sources

Prevalence and Diagnostic Challenge of Hemophagocytic Lymphohistiocytosis Syndrome in Critically Ill Patients

European Journal of Haematology, EarlyView.
ABSTRACT Background Hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome. It is a severe condition with a challenging diagnosis in the intensive care unit (ICU), for which current recommendations rely on fulfilling five of eight HLH‐2004 criteria.
Claire Queffeulou, Mathieu Bellal, Suzanne Goursaud, Sylvain Chantepie, Damien du Cheyron   +4 more
wiley   +1 more source

SPLENOMEGALY [PDF]

BMJ, 1936
openaire   +2 more sources