Results 101 to 110 of about 138,072 (341)

Limited effectiveness of high-dose liposomal amphotericin B (AmBisome) for treatment of visceral leishmaniasis in an Ethiopian population with high HIV prevalence. [PDF]

, 2011
Due to unacceptably high mortality with pentavalent antimonials, Médecins Sans Frontières in 2006 began using liposomal amphotericin B (AmBisome) for visceral leishmaniasis (VL) patients in Ethiopia who were severely ill or positive for human ...
Aderie, Endashaw Mengistu, Chane, Solomon, Collin, Simon M, Davidson, Robert N, Piening, Turid, Ritmeijer, Koert, ter Horst, Rachel   +6 more
core   +2 more sources

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

IRF-5 Expression in Myeloid Cells Is Required for Splenomegaly in L. donovani Infected Mice

Frontiers in Immunology, 2020
Persistent Leishmania donovani infection is characterized by chronic inflammation, immune suppression, and splenomegaly. We have previously reported that the transcription factor interferon regulatory factor 5 (IRF-5) is largely responsible for inducing ...
Linh Thuy Mai, Mélina Smans, Sasha Silva-Barrios, Aymeric Fabié, Simona Stäger   +4 more
doaj   +1 more source

Interleukin‐18 Levels Are Associated With Disease Course in Patients With Still Disease Treated With Interleukin‐1 Inhibitors

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the prognostic utility of circulating interleukin‐18 (IL‐18) levels in predicting disease activity, macrophage activation syndrome (MAS), and disease course in patients with Still disease (SD) receiving first‐line IL‐1 inhibitors (IL‐1i).
Matteo Trevisan, Manuela Pardeo, Ivan Caiello, Claudia Bracaglia, Arianna De Matteis, Valentina Matteo, Elena Loricchio, Fabrizio De Benedetti, Giusi Prencipe   +8 more
wiley   +1 more source

Hairy cell leukemia: A case report of unusual presentation without splenomegaly [PDF]

Medical Laboratory Journal
Hairy cell leukemia (HCL) is characterized by pancytopenia and is usually associated with massive splenomegaly; however, the same may not be true in clinical settings.
Shuchismita ., Iffat Jamal, Vijayanand Choudhary   +2 more
doaj  

Preoperatively diagnosed isolated hydatid cyst of pancreatic head with triad of obstructive jaundice, left-sided portal hypertension and chronic pancreatitis

MAMC Journal of Medical Sciences, 2015
We report a rare case of young female with isolated pancreatic head hydatid cyst causing obstructive jaundice, left-sided portal hypertension, and chronic pancreatitis.
Pradeep Choudhary, Harsh Vardhan Khokhar, Yashant Aswani, Sangeeta Saxena   +3 more
doaj   +1 more source

Response: Accidental Potassium Bromate Poisoning Causing Acute Renal Failure [PDF]

, 2009
No ...
Oshikoya, KA
core   +1 more source

Alopecia, ascites, and incomplete regeneration after 85 to 90 per cent liver resection [PDF]

, 1975
A nineteen year old female underwent 85 to 90 per cent partial hepatectomy to treat a minimal deviation hepatoma. Observations afterwards suggested that the limit of resection compatible with survival had been reached.
Corman, JL, Groth, CG, Putnam, CW, Starzl, TE, Taubman, J   +4 more
core   +1 more source

MPL mutations and palpable splenomegaly are independent risk factors for fibrotic progression in essential thrombocythemia

Blood Cancer Journal, 2016
MPL mutations and palpable splenomegaly are independent risk factors for fibrotic progression in essential ...
M. Haider, Y. Elala, N. Gangat, C. Hanson, A. Tefferi   +4 more
semanticscholar   +1 more source

A Rare RIPK3 Variant Enhances Necroptosis and Promotes Inflammation in a Still Disease–Like Autoinflammatory Syndrome

Arthritis &Rheumatology, EarlyView.
Objective Still disease represents a prototypical polygenic systemic autoinflammatory disease, characterized by recurrent systemic inflammation and dysregulation of innate immunity. Despite extensive clinical characterization, familial clustering Still disease remains unreported.
Longfang Chen, Qihua Dai, Yu Xiao, Jialin Dai, Mengyan Wang, Yuning Ma, Yujie Shen, Zhimo Xu, Jianfen Meng, Xia Chen, Da Yi, Yue Sun, Hui Shi, Honglei Liu, Xiaobing Cheng, Yutong Su, Junna Ye, Huihui Chi, Zhuochao Zhou, Tingting Liu, Jialin Teng, Chengde Yang, Jinchao Jia, Qiongyi Hu   +23 more
wiley   +1 more source