Results 181 to 190 of about 132,601 (358)
Clinical management of CMML—State of the art
British Journal of Haematology, EarlyView.Patients with chronic myelomonocytic leukaemia (CMML) typically present with clinical feature including splenomegaly, constitutional symptoms and autoimmune phenomena, as well as with pathological blood counts and biological features in the marrow. These characteristics may influence the assignment to prognostic categories such as the CPSSmol and also ...
K. Nachtkamp +3 more
wiley +1 more source
Pediatric Gaucher Disease Type 3 Presenting with Oculomotor Apraxia: A Case Report
ChildrenWe report on a 4-year-old boy affected by Gaucher disease (GD) type 3, who presented with splenomegaly and a history of oculomotor apraxia. GD is a rare lysosomal storage disorder caused by glucocerebrosidase deficiency with multi-organ involvement ...
Margherita Di Costanzo +4 more
doaj +1 more source
Effects of Temperature and Crowding on the Pathogenicity of Edwardsiella ictaluri in Channel Catfish (Ictalurus punctatus) [PDF]
, 1985 Channel catfish were injected with Edwardsiella ictaluri and stocked at increasing temperatures and densities. Bacteriological examination of kidney, liver and spleen revealed the greatest numbers of organisms in fish from the highest temperature and ...
Hinck, Lawrence W., Johnson, Sharon L.
core +2 more sources
Primary myelofibrosis with increased haemoglobin concentration at presentation
British Journal of Haematology, EarlyView.Subjects with primary myelofibrosis and elevated haemoglobin levels at diagnosis tend to have longer survival rates (OS) and blast transformation‐free survival (BTFS) than those with normal or reduced haemoglobin levels. Summary One hundred of 963 consecutive registrants with primary myelofibrosis (PMF) in the Pavia‐CSM database had haemoglobin ...
Giovanni Barosi +8 more
wiley +1 more source
Gaucher’s Disease – What Should You Know
Quality in SportGaucher’s Disease (GD) has a special place among ultra-rare diseases, which is a disease that occurs in less than onein 50 000 persons. The disease is caused by a hereditary autosomal deficiency of the lysosomal enzyme glucocerebrosidase.
Dominika Podgórska +7 more
doaj +1 more source
Clinical Case ReportsKey Clinical Message When a person has both HS and beta‐thalassemia, their clinical symptoms tend to be less severe. This is because these two conditions have contrasting features.
Sana Habibzadeh +4 more
doaj +1 more source
Protein tyrosine phosphatases as emerging targets for cancer immunotherapy
British Journal of Pharmacology, EarlyView.Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley +1 more source