Results 11 to 20 of about 138,072 (341)

Splenomegaly impacts prognosis in essential thrombocythemia and polycythemia vera: A single center study [PDF]

open access: yesHematology Reports, 2019
Splenomegaly is one of the major clinical manifestations of primary myelofibrosis and is common also in other chronic Philadelphia-negative myeloproliferative neoplasms, causing symptoms and signs and affecting quality of life of patients diagnosed with ...
Accurso V.   +8 more
core   +2 more sources

Splenomegaly in Children and Adolescents

open access: yesFrontiers in Pediatrics, 2021
In contrast to other lymphoid tissues making up the immune system, the spleen as its biggest organ is directly linked into the blood circulation. Beside its main task to filter out microorganism, proteins, and overaged or pathologically altered blood ...
Meinolf Suttorp   +2 more
doaj   +2 more sources

Investigation and Analysis of Iron-Deficiency Anemia Complicated by Splenomegaly

open access: yesInternational Journal of General Medicine, 2021
Yan-hui Wei,1 Yu-zhuo He,2 Xiao-yan Guo,1 Xiao-yan Lin,2 Hong-bin Zhu,2 Xue-jun Guo2 1Department of Graduate School, Xinxiang Medical University, Xinxiang, Henan Province, 453003, People’s Republic of China; 2Department of Hematology, Puyang Oilfield ...
Wei Y, He Y, Guo X, Lin X, Zhu H, Guo X
doaj   +2 more sources

Volumetric Splenomegaly in Patients With Polycythemia Vera

open access: yesJournal of Korean medical science, 2022
Background Non-palpable splenomegaly in patients with polycythemia vera (PV) has seldom been addressed. In this retrospective study, we evaluated non-palpable, volumetric splenomegaly defined based on age- and body surface area (BSA)–matched criteria in ...
Myung-Won Lee   +9 more
semanticscholar   +1 more source

Predicting the probability of Gaucher disease in subjects with splenomegaly and thrombocytopenia

open access: yesScientific Reports, 2021
Hematologists are frequently involved in the diagnostic pathway of Gaucher disease type 1 (GD1) patients since they present several hematological signs. However, GD1 is mainly underdiagnosed because of a lack of awareness.
I. Motta   +35 more
semanticscholar   +1 more source

Predominant Role of Immunoglobulin G in the Pathogenesis of Splenomegaly in Murine Lupus

open access: yesFrontiers in Immunology, 2020
Systemic lupus erythematosus (SLE) is characterized by high levels of autoantibodies and multiorgan tissue damage. The pathogenesis of splenomegaly in SLE remains unknown. In this study, the role of immunoglobulin G (IgG) generation and deposition in the
Qian Zhang   +5 more
semanticscholar   +1 more source

Incidentally Detected Celiac Disease with Splenomegaly on 18F FDG PET/CT: A Potential Lymphoma Mimic [PDF]

open access: yesAsia Oceania Journal of Nuclear Medicine and Biology, 2021
Celiac disease is an immune-mediated disorder triggered by hypersensitivity to gluten occurring in genetically susceptible individuals. A high-index of suspicion is needed for diagnosis as patients can be asymptomatic or present with atypical symptoms or
Ananya Panda   +5 more
doaj   +1 more source

Retained splenic function in an indian population with homozygous sickle cell disease may have important clinical significance

open access: yesIndian Journal of Community Medicine, 2021
Background and Objectives: To determine whether the persistence of splenomegaly characteristic of the Asian haplotype of homozygous sickle cell (SS) disease is associated with continued splenic function, a comparison of patients from Odisha, India, and ...
Beryl Serjeant   +2 more
doaj   +1 more source

PRIMARY BILIARY CHOLANGITIS DIAGNOSIS IN A SERONEGATIVE 19-YEAR-OLD WOMAN [PDF]

open access: yesEuromediterranean Biomedical Journal, 2023
Primary biliary cholangitis (PBC) is an autoimmune disease that destroys small bile ducts, culminating in liver failure. It typically affects middle-aged, Caucasian women. Most cases have detectable antimitochondrial antibodies.
Sara Santos
doaj   +1 more source

Oxaliplatin-induced haematological toxicity and splenomegaly in mice

open access: yesPLoS ONE, 2020
Purpose Haematological toxicities occur in patients receiving oxaliplatin. Mild anaemia (grade 1–2) is a common side effect and approximately 90% of recipients develop measurable spleen enlargement.
J. Lees   +6 more
semanticscholar   +1 more source

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