Results 231 to 240 of about 129,482 (378)

Immunological studies in tropical splenomegaly syndrome in Uganda [PDF]

, 1969
John L. Ziegler, Martin H. Cohen, M. S. R. Hutt   +2 more
openalex   +1 more source

Acute splenomegaly, haemolysis, and thrombocytopenia following luspatercept initiation in a patient with transfusion‐dependent thalassaemia: A case report

British Journal of Haematology, EarlyView.
Summary Patients with transfusion‐dependent thalassaemia (TDT) require chronic, life‐sustaining red blood cell transfusions, which contribute to iron overload and associated morbidity and mortality. Luspatercept, an inhibitor of the transforming growth factor‐beta pathway, decreases transfusion requirements in a subset of transfusion‐dependent β ...
Bianca Zaidel, Stephanie Garland, Hayley Merkeley   +2 more
wiley   +1 more source

Splenomegaly, elevated alkaline phosphatase and mutations in the SRSF2/ASXL1/RUNX1 gene panel are strong adverse prognostic markers in patients with systemic mastocytosis

Leukemia, 2016
M. Jawhar, J. Schwaab, D. Hausmann, J. Clemens, N. Naumann, T. Henzler, H. Horny, Karl Sotlar, Stefan O. Schoenberg, N. Cross, N. Cross, A. Fabarius, W. Hofmann, P. Valent, G. Metzgeroth, A. Reiter   +15 more
semanticscholar   +1 more source

Real World Management of Cytopenias and Infections in Patients With Myelofibrosis Treated With Ruxolitinib. [PDF]

EJHaem
Butler LA, Forsyth C, Harrison C, Perkins AC.   +3 more
europepmc   +1 more source

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

British Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

Preoperative high-precision three-dimensional reconstruction in laparoscopic splenectomy for supramassive splenomegaly: a case report and literature review. [PDF]

Front Med (Lausanne)
Huang C, Gao Z, Zhang Y, Ge L.
europepmc   +1 more source

Operative treatment of splenomegaly. E. Weil and Grégoire (Pr. med., 1927, No. 60)

, 1928
N. Kramov
openalex   +2 more sources

GGCT Inhibits Ferroptosis in PTC Cells by Upregulating p53 Through RPS15A

Cancer Science, EarlyView.
Our results showed that γ‐glutamine cyclotransferase (GGCT) knockdown in PTC cells inhibited GSH synthesis, promoted the malignant accumulation of malondialdehyde (MDA) and reactive oxygen species (ROS), and finally promoted cell ferroptosis. In vivo experiments showed that Pro‐GA, a specific inhibitor of GGCT, inhibited the subcutaneous tumorigenesis ...
Hui‐min Zhang, Han‐ning Li, Enbo Qi, Yang Yang, Huiping Ma, Jie Ma, Xiwen Xiong, Jun Wang, Zhi‐fang Yang, Xing‐hua Liao   +9 more
wiley   +1 more source

Partial splenectomy for massive malarial splenomegaly: A unique case from an Australian regional centre. [PDF]

Int J Surg Case Rep
Lalloz M, Swift K, Mouline O, Beardsley C.   +3 more
europepmc   +1 more source

Gaucher Disease: A First Reported Adult Case in Indonesia

Acta Medica Indonesiana
A 44-year-old female presented with a distended abdomen and fatigue. On physical examination, prominent splenomegaly was found. The laboratory investigations revealed pancytopenia and decreased albumin-globulin ratio.
Ardhi Rahman Ahani, Cosphiadi Irawan, Agnes Stephanie Harahap, Klara Yuliarti, Maria Francisca Ham, Faramitha Nur Izzaty, Damayanti Rusli Sjarif   +6 more
doaj