Results 281 to 290 of about 138,072 (341)

Fetal Splenomegaly

Ultrasound Quarterly, 2018
Abstract Enlargement of the fetal spleen is usually found secondary to systemic diseases and is frequently associated with hepatomegaly. By far, the most common causes of fetal splenomegaly are infectious. Other etiologies responsible for this sign are hemolytic anemia, congestive cardiac failure, metabolic disorders, and rarely, leukemia ...
Marta, Moreira, Rafael, Brás, Daniela, Gonçalves, Inês, Alencoão, Gonçalo, Inocêncio, Maria, Rodrigues, Jorge, Braga   +6 more
openaire   +3 more sources

Splenomegaly in patients with primary or secondary myelofibrosis who are candidates for allogeneic hematopoietic cell transplantation: a Position Paper on behalf of the Chronic Malignancies Working Party of the EBMT.

The Lancet Haematology, 2022
Splenomegaly is a hallmark of myelofibrosis, a debilitating haematological malignancy for which the only curative option is allogeneic haematopoietic cell transplantation (HCT).
N. Polverelli, J. Hernández-Boluda, T. Czerw, T. Barbui, M. D'adda, H. Deeg, M. Ditschkowski, C. Harrison, N. Kröger, R. Mesa, F. Passamonti, F. Palandri, N. Pemmaraju, U. Popat, D. Rondelli, A. Vannucchi, S. Verstovsek, M. Robin, A. Colecchia, L. Grazioli, E. Damiani, D. Russo, J. Brady, D. Patch, S. Blamek, G. Damaj, P. Hayden, D. Mclornan, I. Yakoub-Agha   +28 more
semanticscholar   +1 more source

Ruxolitinib for the treatment of inadequately controlled polycythaemia vera without splenomegaly (RESPONSE-2): a randomised, open-label, phase 3b study

Lancet Oncology, The, 2017
BACKGROUND In the pivotal RESPONSE study, ruxolitinib, a Janus kinase (JAK)1 and JAK2 inhibitor, was superior to best available therapy at controlling haematocrit and improving splenomegaly and symptoms in patients with polycythaemia vera with ...
Francesco Passamonti, Francesca Palandri, Giulia Benevolo   +2 more
exaly   +2 more sources

Splenomegaly

British Journal of Hospital Medicine, 2011
Splenomegaly is a common finding on clinical examination, and frequently features in postgraduate assessments. The spleen does not normally descend below the left costal margin. The routine abdominal examination will identify whether the spleen is palpable, and if so splenomegaly is almost universally present.
Nicholas F, Brown, Daniel J B, Marks, Philip J, Smith, Stuart L, Bloom   +3 more
openaire   +3 more sources

Splenomegaly

Pediatric Care Online, 2021
Key Points A palpable spleen may be normal, especially in neonates and infants.Because an enlarged spleen can extend into the pelvis, palpation should begin in the right lower quadrant and move across the abdomen toward the left upper quadrant.Viral infection is the most common cause of splenomegaly in children.Splenomegaly from ...
openaire   +1 more source

Ruxolitinib Rechallenge Can Improve Constitutional Symptoms and Splenomegaly in Patients With Myelofibrosis: A Case Series

Clinical Lymphoma, Myeloma & Leukemia, 2018
&NA; There are no approved treatment options for patients with myelofibrosis in whom ruxolitinib fails or ceases to control symptoms and splenomegaly.
A. Gerds, D. Su, A. Martynova, Benjamin Pannell, S. Mukherjee, Caitlin O'Neill, M. Sekeres, C. O'Connell   +7 more
semanticscholar   +1 more source

Hyperreactive malarious splenomegaly (tropical splenomegaly syndrome)

Parasitology Today, 1986
Hyperreactive malarious splenomegaly (HMS), formerly known as tropical splenomegaly syndrome (TSS), was recognized some 20 years ago as an entity distinct from the splenic enlargement resulting directly from malarial parasitaemia. Its basis appears to be a disturbance in the T-lymphocyte control of the humoral response to recurrent malaria, possibly ...
openaire   +2 more sources

Splenomegaly: A Combined Clinical and Radiologic Approach to the Differential Diagnosis.

Gastroenterology Clinics of North America, 2018
An enlarged spleen (splenomegaly) is a common imaging finding and may be related to a broad array of underlying conditions. The multifaceted functions of the spleen make it susceptible to involvement by a variety of pathophysiologic processes ...
B. Sjoberg, C. Menias, M. Lubner, V. Mellnick, P. Pickhardt   +4 more
semanticscholar   +1 more source

Robotic vs laparoscopic splenectomy for splenomegaly: A retrospective comparative cohort study.

International Journal of Surgery, 2018
BACKGROUND The aim of this study was to evaluate the role of robotic total splenectomy for splenomegaly, comparing this approach with the laparoscopic technique.
D. Cavaliere, L. Solaini, D. Di Pietrantonio, F. D’acapito, F. Tauceri, M. Framarini, G. Ercolani   +6 more
semanticscholar   +1 more source

Splenomegaly

Abstract This chapter guides the reader on the diagnosis and management of splenomegaly in hospitalized patients.
Lindel Dewberry, Mackenzie Donoho
  +4 more sources