Results 301 to 310 of about 99,296 (339)

Role of STING Deficiency in Amelioration of Mouse Models of Lupus and Atherosclerosis

Arthritis &Rheumatology, Volume 77, Issue 5, Page 547-559, May 2025.
Objective Systemic lupus erythematosus (SLE) is a systemic autoimmune syndrome characterized by autoreactive responses to nucleic acids, dysregulation of the type I interferon (IFN‐I) pathway, and accelerated atherosclerosis. The stimulator of IFN genes (STING), a cytosolic DNA sensor, has pathogenic implications in various inflammatory diseases ...
Yudong Liu, Carmelo Carmona‐Rivera, Nickie L. Seto, Christopher B. Oliveira, Eduardo Patino‐Martinez, Yvonne Baumer, Tiffany M. Powell‐Wiley, Nehal Mehta, Sarfaraz Hasni, Xuan Zhang, Mariana J. Kaplan   +10 more
wiley   +1 more source

Real-world treatment patterns and health outcomes for patients with myelofibrosis treated with fedratinib. [PDF]

Future Oncol
Passamonti F, Korgaonkar S, Parikh RC, Chevli M, Yucel A, Rombi J, Jones S, Zissler D, Davis KL, Slaff S.   +9 more
europepmc   +1 more source

Sustained efficacy and detailed clinical follow-up of first-line ibrutinib treatment in older patients with chronic lymphocytic leukemia: Extended phase 3 results from RESONATE-2 [PDF]

, 2018
Bartlett, Nancy L, et al.,
core   +1 more source

Transcutaneous Imiquimod Combined With Anti‐Programmed Cell Death‐1 Monoclonal Antibody Extends the Survival of Mice Bearing Renal Cell Carcinoma

Cancer Medicine, Volume 14, Issue 10, May 2025.
ABSTRACT Purpose Imiquimod (IQM), an imidazoquinoline derivative, is an immunomodulator that activates an adaptive immune response. IQM is applied topically for genital warts and actinic keratosis. Programmed cell death‐1 (PD‐1) suppresses activated T cells by binding to programmed cell death‐ligand 1 and programmed cell death‐ligand 2, braking ...
Takashi Karashima, Toshihiro Komatsu, Shinkuro Yamamoto, Kaya Atagi, Hatsune Hashida, Hideo Fukuhara, Kenji Tamura, Shingo Ashida, Taro Shuin, Keiko Udaka, Takahiro Shimizu, Motoaki Saito, Nobutaka Shimizu, Keiji Inoue   +13 more
wiley   +1 more source

Acinetobacter‐Induced Endocarditis Post Cupping Therapy: Case Report

Clinical Case Reports, Volume 13, Issue 5, May 2025.
ABSTRACT Acinetobacter‐induced endocarditis, though rare and typically associated with immunocompromised patients, can occur in healthy individuals. This case underscores the importance of considering uncommon pathogens and detailed patient histories, particularly following procedures such as cupping therapy, in the diagnosis of endocarditis.
Fateh Kashkash, Sarya Swed, Ali Mustafa, Saleh Azizi, Agyad Bakkour, Ahmad Abdalla, Mohammad Alkammar, Wael Hafez   +7 more
wiley   +1 more source

Association between Loa loa microfilaremia and anatomical hyposplenia in a rural area of the Republic of Congo: a population-based cross-sectional study. [PDF]

Infect Dis Poverty
Boullé C, Lebredonchel E, Campillo JT, Dupasquier V, Hemilembolo MC, Pion SDS, Djontu JC, Rancé L, Souteyrand P, Missamou F, Boussinesq M, Ntoumi F, Chesnais CB.   +12 more
europepmc   +1 more source

Regulation and Function of the Atypical IκBs—Bcl‐3, IκBNS, and IκBζ—in Lymphocytes and Autoimmunity

European Journal of Immunology, Volume 55, Issue 5, May 2025.
This review article summarizes the currently available information on the functions of atypical IκB proteins including Bcl‐3, IκBNS, and IκBζ, which have been studied mostly in mouse models. We focus on the regulation of these modulators of transcription, describe their role in lymphocyte differentiation, and their involvement in the development of ...
Tanja Kübelbeck, Nina Olivera Wichmann, Timsse Raj, Cynthia Raj, Caspar Ohnmacht, Nadine Hövelmeyer, Daniela Kramer, Vigo Heissmeyer   +7 more
wiley   +1 more source

The Risk Factors of Refractory Adult-Onset Still's Disease. [PDF]

Int J Hepatol
Cheng L, Zong H, Li D, Zhang Y, Qian L.
europepmc   +1 more source

Scrub Typhus in Kerala: Demographic, Clinical, and Laboratory Predictors of ICU Admission in a Tertiary Care Setting. [PDF]

Infez Med
Saheed SZ, Goswami D, Niyas VKM, Ananthanaryanan R.   +3 more
europepmc   +1 more source