Results 41 to 50 of about 129,482 (378)
Overexpression of Mcl-1 exacerbates lymphocyte accumulation and autoimmune kidney disease in lpr mice [PDF]
, 2016 Cell death by apoptosis has a critical role during embryonic development and in maintaining tissue homeostasis. In mammals,
there are two converging apoptosis pathways: the ‘extrinsic’ pathway, which is triggered by engagement of cell surface ‘death ...Anstee, Natasha S., Vandenberg, Cassandra J., Campbell, Kirsteen J., Hughes, Peter D., O’Reilly, Lorraine A., Cory, Suzanne +5 morecore +7 more sourcesRIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease
Hepatology, EarlyView., 2022 RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims
Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)Marta B. Afonso, Tawhidul Islam, Julie Magusto, Ricardo Amorim, Véronique Lenoir, Rui F. Simões, José Teixeira, Liana C. Silva, Dominique Wendum, Isabelle Jéru, Corinne Vigouroux, Rui E. Castro, Paulo J. Oliveira, Carina Prip‐Buus, Vlad Ratziu, Jérémie Gautheron, Cecília M. P. Rodrigues +16 morewiley +1 more sourceIsolated hepatic sarcoidosis [PDF]
Vojnosanitetski Pregled, 2014 Introduction. Sarcoidosis is a multisystem granulomatous disease of unknown
etiology. Although hepatic granulomas occur in 50-65% of patients with
systemic sarcoidosis, isolated liver sarcoidosis is rare.Jovičić Ivana, Popović Dušan Đ., Tončev Ljubiša, Jovičić Žikica, Vučinić Violeta, Kovačević Nada, Đuranović Srđan, Boričić Ivan, Micev Marjan, Špuran Milan, Milosavljević Tomica +10 moredoaj +1 more sourcePresenting signs and patient co-variables in Gaucher disease : outcome of the Gaucher Earlier Diagnosis Consensus (GED-C) Delphi initiative [PDF]
, 2019 © 2018 The Authors. Internal Medicine Journal by Wiley Publishing Asia Pty Ltd on behalf of Royal Australasian College of Physicians.Background: Gaucher disease (GD) presents with a range of signs and symptoms.Belmatoug , N, Bembi , B, Bright, J, Deodato, F, Di Rocco, M, Goker-Alpan, O, Hughes, DA, Kuter, David, Lukina, EA, Machaczka, M, Mehta, Atul, Mengel, E, Nagral, A, Nakamura, K, Narita, A, Oliveri , B, Pastores, G, Pérez-López, J, Ramaswami, U, Salek, Mir-Saeed Shayegan, Schwartz, IV, Szer, J, Vom Dahl, S, Weinreb, NJ, Zimran, A +24 morecore +5 more sourcesNatural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study
Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims
Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.Shannon M. Vandriel, Li‐Ting Li, Huiyu She, Jian‐She Wang, Melissa A. Gilbert, Irena Jankowska, Piotr Czubkowski, Dorota Gliwicz‐Miedzińska, Emmanuel M. Gonzales, Emmanuel Jacquemin, Jérôme Bouligand, Nancy B. Spinner, Kathleen M. Loomes, David A. Piccoli, Lorenzo D'Antiga, Emanuele Nicastro, Étienne Sokal, Tanguy Demaret, Noelle H. Ebel, Jeffrey A. Feinstein, Rima Fawaz, Silvia Nastasio, Florence Lacaille, Dominique Debray, Henrik Arnell, Björn Fischler, Susan Siew, Michael Stormon, Saul J. Karpen, Rene Romero, Kyung Mo Kim, Woo Yim Baek, Winita Hardikar, Sahana Shankar, Amin J. Roberts, Helen M. Evans, M. Kyle Jensen, Marianne Kavan, Shikha S. Sundaram, Alexander Chaidez, Palaniswamy Karthikeyan, Maria Camila Sanchez, Maria Lorena Cavalieri, Henkjan J. Verkade, Way Seah Lee, James E. Squires, Christina Hajinicolaou, Chatmanee Lertudomphonwanit, Ryan T. Fischer, Catherine Larson‐Nath, Yael Mozer‐Glassberg, Cigdem Arikan, Henry C. Lin, Jesus Quintero Bernabeu, Seema Alam, Deirdre A. Kelly, Elisa Carvalho, Cristina Targa Ferreira, Giuseppe Indolfi, Ruben E. Quiros‐Tejeira, Pinar Bulut, Pier Luigi Calvo, Zerrin Önal, Pamela L. Valentino, Dev M. Desai, John Eshun, Maria Rogalidou, Antal Dezsőfi, Sabina Wiecek, Gabriella Nebbia, Raquel Borges Pinto, Victorien M. Wolters, María Legarda Tamara, Andréanne N. Zizzo, Jennifer Garcia, Kathleen Schwarz, Marisa Beretta, Thomas Damgaard Sandahl, Carolina Jimenez‐Rivera, Nanda Kerkar, Jernej Brecelj, Quais Mujawar, Nathalie Rock, Cristina Molera Busoms, Wikrom Karnsakul, Eberhard Lurz, Ermelinda Santos‐Silva, Niviann Blondet, Luis Bujanda, Uzma Shah, Richard J. Thompson, Bettina E. Hansen, Binita M. Kamath, The Global ALagille Alliance (GALA) Study Group +93 morewiley +1 more sourceDeclining Burden of Malaria Over two Decades in a Rural Community of Muheza District, North-Eastern Tanzania. [PDF]
, 2013 The recently reported declining burden of malaria in some African countries has been attributed to scaling-up of different interventions although in some areas, these changes started before implementation of major interventions.A Bhattarai, AC Ghani, AM Ronn, AS Rutta, BA Okech, BL Sharp, BP Mmbando, Bruno P Mmbando, C Karema, C Lengeler, Deus S Ishengoma, DS Ishengoma, DW Meyrowitsch, E Chizema-Kawesha, EA Okiro, EA Okiro, FO ter Kuile, G Mtove, G O'Connor, H Reyburn, HD Teklehaimanot, I Kleinschmidt, I Kleinschmidt, Ib C Bygbjerg, J Mufunda, J Picard, JC Beier, JP Lusingu, KI Barnes, M Alifrangis, M Lemnge, M Otten, Martha M Lemnge, Method D Segeja, MH Craig, MH Craig, Michael Alifrangis, Ministry of Health, Ministry of Health, MK Bouyou-Akotet, MM Lemnge, MM Lemnge, MS Hsiang, MW Aregawi, National Malaria Control Programme, P Chanda, P Winskill, PH Jakobsen, PM Graves, PM Nyarango, R Maharaj, RJ Manuel, RW Steketee, SJ Ceesay, SJ Ceesay, SM Magesa, T Bousema, T Jelinek, T Jelinek, VA Kilimali, WHO, WHO, WHO, WP O'Meara, WP O'Meara, YA Derua +65 morecore +2 more sourcesInterleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Hepatology, EarlyView., 2022 Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims
Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.Jana Knorr, Benedikt Kaufmann, Maria Eugenia Inzaugarat, Theresa Maria Holtmann, Lukas Geisler, Jana Hundertmark, Marlene Sophia Kohlhepp, Laela M. Boosheri, Daisy R. Chilin‐Fuentes, Amanda Birmingham, Kathleen M. Fisch, Joel D. Schilling, Sven H. Loosen, Christian Trautwein, Christoph Roderburg, Münevver Demir, Frank Tacke, Hal M. Hoffman, Ariel E. Feldstein, Alexander Wree +19 morewiley +1 more sourceEpidemiology of malaria in the Taabo health and demographic surveillance system, south-central Côte d'Ivoire [PDF]
, 2016 A deep understanding of the local epidemiology of malaria is essential for the design and implementation of setting-specific control and elimination efforts.Adiossan, Lukas G., Baikoro, Nahoua, Bassa, Fidèle K., Bonfoh, Bassirou, Koné, Siaka, N'Cho, Moussan, N'Goran, Eliézer K., Ouattara, Mamadou, Silué, Kigbafori D., Traoré, Mahamadou, Utzinger, Jürg +10 morecore +2 more sourcesCD11b+CD43hiLy6Clo splenocyte‐derived macrophages exacerbate liver fibrosis via spleen–liver axis
Hepatology, EarlyView., 2022 A population of splenic monocytes migrate into the liver and shift to macrophages, which account for the exacerbation of liver fibrosis. Abstract Background and Aims
Monocyte‐derived macrophages (MoMFs), a dominant population of hepatic macrophages under inflammation, play a crucial role in liver fibrosis progression.Shaoying Zhang, Dan Wan, Mengchen Zhu, Guihu Wang, Xurui Zhang, Na Huang, Jian Zhang, Chongyu Zhang, Qi Shang, Chen Zhang, Xi Liu, Fanfan Liang, Chunyan Zhang, Guangyao Kong, Jing Geng, Libo Yao, Shemin Lu, Yongyan Chen, Zongfang Li +18 morewiley +1 more source
