A case report of a pregnant woman with compensated liver cirrhosis and pancytopenia
Key Clinical Message Liver cirrhosis may worsen during pregnancy resulting in adverse maternal and fetal outcomes. Proper antenatal evaluation, staging, and variceal screening will facilitate the management.
Sreenisha S. S+3 more
doaj +1 more source
We tested the effect of exercise training and genistein treatment on splenomegaly in mice fed a high-fat, high-sugar diet (HFSD). Male and female C57BL6 mice fed HFSD containing 60% fat along with drinking water containing 42 g/L sugar (55% sucrose/45 ...
Levi Buchan+7 more
semanticscholar +1 more source
IRF-5 Expression in Myeloid Cells Is Required for Splenomegaly in L. donovani Infected Mice
Persistent Leishmania donovani infection is characterized by chronic inflammation, immune suppression, and splenomegaly. We have previously reported that the transcription factor interferon regulatory factor 5 (IRF-5) is largely responsible for inducing ...
Linh Thuy Mai+4 more
doaj +1 more source
Low prevalence of an acute phase response in asymptomatic children from a malaria-endemic area of Papua New Guinea [PDF]
Levels of C-reactive protein (CRP), a classic marker for the acute phase response (APR), were measured in children with asymptomatic malaria infection in the Amele region of Papua New Guinea (PNG).
Day, KP+6 more
core
Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function
CYTOR is a pro‐myogenic ncRNA in skeletal muscle. Here, chemical probing of CYTOR, coupled with functional cellular assays identifies exon 2 as an independent myogenic RNA domain. Chemical engineering of CYTOR exon 2 RNA improves pharmacologic properties, including RNA stability and cell‐autonomous immunogenicity.
Zeinabou Niasse‐Sy+6 more
wiley +1 more source
Evaluation of Hepatosplenomegaly and Liver Function Tests in 102 Brucellosis Cases [PDF]
Introduction: Brucellosis is a systemic infection which in volves many organs including liver. In this study, it was aimed to review the hepatosplenic findings in allcases followed up in our clinic with the diagnosis of brucellosis.
Serhat UYSAL+7 more
doaj +1 more source
Primary splenic diffuse large B-cell lymphoma: a case report
Primary splenic lymphoma (PSL) is a rare disease and an improbable cause of splenomegaly or splenic nodules. On the contrary, splenic secondary involvement as part of an advanced lymphoproliferative disorder is more common.
Nuno Maia Neves+5 more
doaj +1 more source
Idiopathic noncirrhotic portal hypertension: current perspectives [PDF]
The term idiopathic noncirrhotic portal hypertension (INCPH) has been recently proposed to replace terms, such as hepatoportal sclerosis, idiopathic portal hypertension, incomplete septal cirrhosis, and nodular regenerative hyperplasia, used to describe ...
D'AMATI, Giulia+5 more
core +1 more source
The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction
Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang+8 more
wiley +1 more source
Case report of an enigmatic childhood hematomalignancy
Juvenile Myelomonocytic Leukemia (JMML) is a rare leukemia of children we are still in the process of unraveling presenting a frustrating and dismal picture.
M Geetha+5 more
doaj +1 more source