Results 71 to 80 of about 129,482 (378)

A case report of a pregnant woman with compensated liver cirrhosis and pancytopenia

open access: yesClinical Case Reports, 2023
Key Clinical Message Liver cirrhosis may worsen during pregnancy resulting in adverse maternal and fetal outcomes. Proper antenatal evaluation, staging, and variceal screening will facilitate the management.
Sreenisha S. S   +3 more
doaj   +1 more source

High-fat, high-sugar diet induces splenomegaly that is ameliorated with exercise and genistein treatment

open access: yesBMC Research Notes, 2018
We tested the effect of exercise training and genistein treatment on splenomegaly in mice fed a high-fat, high-sugar diet (HFSD). Male and female C57BL6 mice fed HFSD containing 60% fat along with drinking water containing 42 g/L sugar (55% sucrose/45 ...
Levi Buchan   +7 more
semanticscholar   +1 more source

IRF-5 Expression in Myeloid Cells Is Required for Splenomegaly in L. donovani Infected Mice

open access: yesFrontiers in Immunology, 2020
Persistent Leishmania donovani infection is characterized by chronic inflammation, immune suppression, and splenomegaly. We have previously reported that the transcription factor interferon regulatory factor 5 (IRF-5) is largely responsible for inducing ...
Linh Thuy Mai   +4 more
doaj   +1 more source

Low prevalence of an acute phase response in asymptomatic children from a malaria-endemic area of Papua New Guinea [PDF]

open access: yes, 2007
Levels of C-reactive protein (CRP), a classic marker for the acute phase response (APR), were measured in children with asymptomatic malaria infection in the Amele region of Papua New Guinea (PNG).
Day, KP   +6 more
core  

Delivery of A Chemically Modified Noncoding RNA Domain Improves Dystrophic Myotube Function

open access: yesAdvanced Science, EarlyView.
CYTOR is a pro‐myogenic ncRNA in skeletal muscle. Here, chemical probing of CYTOR, coupled with functional cellular assays identifies exon 2 as an independent myogenic RNA domain. Chemical engineering of CYTOR exon 2 RNA improves pharmacologic properties, including RNA stability and cell‐autonomous immunogenicity.
Zeinabou Niasse‐Sy   +6 more
wiley   +1 more source

Evaluation of Hepatosplenomegaly and Liver Function Tests in 102 Brucellosis Cases [PDF]

open access: yesMediterranean Journal of Infection, Microbes and Antimicrobials, 2014
Introduction: Brucellosis is a systemic infection which in volves many organs including liver. In this study, it was aimed to review the hepatosplenic findings in allcases followed up in our clinic with the diagnosis of brucellosis.
Serhat UYSAL   +7 more
doaj   +1 more source

Primary splenic diffuse large B-cell lymphoma: a case report

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2023
Primary splenic lymphoma (PSL) is a rare disease and an improbable cause of splenomegaly or splenic nodules. On the contrary, splenic secondary involvement as part of an advanced lymphoproliferative disorder is more common.
Nuno Maia Neves   +5 more
doaj   +1 more source

Idiopathic noncirrhotic portal hypertension: current perspectives [PDF]

open access: yes, 2016
The term idiopathic noncirrhotic portal hypertension (INCPH) has been recently proposed to replace terms, such as hepatoportal sclerosis, idiopathic portal hypertension, incomplete septal cirrhosis, and nodular regenerative hyperplasia, used to describe ...
D'AMATI, Giulia   +5 more
core   +1 more source

The Role of MCPIP1 in Macrophage Polarization and Cardiac Function Post‐Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
Following myocardial infarction, MCPIP1 deficiency in macrophages triggers ferroptosis, driving proinflammatory M1 dominance over reparative M2 phenotypes. This imbalance amplifies splenic monocyte release and sustains cardiac inflammation. Concurrently, excessive inflammatory mediators and insufficient TGF‐β impair fibroblast activation, delaying ...
Xingxu Zhang   +8 more
wiley   +1 more source

Case report of an enigmatic childhood hematomalignancy

open access: yesJournal of Pediatric Critical Care, 2019
Juvenile Myelomonocytic Leukemia (JMML) is a rare leukemia of children we are still in the process of unraveling presenting a frustrating and dismal picture.
M Geetha   +5 more
doaj   +1 more source

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