Results 71 to 80 of about 68,138 (263)
Prevalence of Gaucher’s Disease in a Hematology Outpatient Clinic
Journal of Contemporary Medicine, 2020 Objective: Gaucher’s disease (GD) is a disease caused by glucocerebrosidase enzyme deficiency and characterized by glucoceramide accumulation in the reticuloendothelial system.
Didar Yanardağ Açık, Bilal Aygun
doaj +1 more source
A case report of a pregnant woman with compensated liver cirrhosis and pancytopenia
Clinical Case Reports, 2023 Key Clinical Message Liver cirrhosis may worsen during pregnancy resulting in adverse maternal and fetal outcomes. Proper antenatal evaluation, staging, and variceal screening will facilitate the management.
Sreenisha S. S +3 more
doaj +1 more source
Arthritis &Rheumatology, EarlyView.Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi +9 more
wiley +1 more source
IRF-5 Expression in Myeloid Cells Is Required for Splenomegaly in L. donovani Infected Mice
Frontiers in Immunology, 2020 Persistent Leishmania donovani infection is characterized by chronic inflammation, immune suppression, and splenomegaly. We have previously reported that the transcription factor interferon regulatory factor 5 (IRF-5) is largely responsible for inducing ...
Linh Thuy Mai +4 more
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From Interferon Signature to the Clinical Landscape: Type I Interferonopathies
Arthritis &Rheumatology, EarlyView.Objective TypeI interferonopathies are heterogeneous diseases driven by dysregulated type I interferon (IFN‐I) signaling. Diagnosis is challenging due to clinical/molecular variability and the need for IFN‐I quantification. The aim of this study was to characterize the clinical, immunologic, genetic, molecular profiles of patients with suspected ...
Ismail Yaz +13 more
wiley +1 more source
Hairy cell leukemia: A case report of unusual presentation without splenomegaly [PDF]
Medical Laboratory JournalHairy cell leukemia (HCL) is characterized by pancytopenia and is usually associated with massive splenomegaly; however, the same may not be true in clinical settings.
Shuchismita . +2 more
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MAMC Journal of Medical Sciences, 2015 We report a rare case of young female with isolated pancreatic head hydatid cyst causing obstructive jaundice, left-sided portal hypertension, and chronic pancreatitis.
Pradeep Choudhary +3 more
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Lymphadenopathy and Splenomegaly
, 2005 Lymphadenopathy and splenomegaly are benign and malignant processes that can produce common findings in children and it is important to distinguish between the two so that appropriate management can be undertaken. Lymphadenopathy might be caused by proliferation of cells intrinsic to the node, such as lymphocytes, plasma cells, monocytes or histiocytes
openaire +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims Glycogen storage disease type Ib (GSD‐Ib) is a rare genetic disorder causing neutropenia and neutrophil dysfunction in children. G‐CSF has been the primary treatment, but emerging data support the potential of empagliflozin, an SGLT2 inhibitor, as a promising investigational option.
Elizabeth Iwasyk +5 more
wiley +1 more source
Case report of an enigmatic childhood hematomalignancy
Journal of Pediatric Critical Care, 2019 Juvenile Myelomonocytic Leukemia (JMML) is a rare leukemia of children we are still in the process of unraveling presenting a frustrating and dismal picture.
M Geetha +5 more
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