Results 51 to 60 of about 13,315 (265)

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

Advanced Science, EarlyView.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen, Rui Liu, Yuan Zhou, Yin Xiao, Chengmin Feng, Lin Chen, Yanshi Li, Mengna Wang, Zhaobo Cheng, Yuxi Luo, Long Liu, Lijing Niu, Yue Xiang, Juan Peng, Guohua Hu, Min Pan   +15 more
wiley   +1 more source

ANALYSIS OF EFFECTIVENESS OF THE MECHANICAL SHOCK ABSORBER PERFORMANCE

Известия высших учебных заведений: Нефть и газ, 2015
A design and the results of testing the mechanical shock absorber containing a body, in the bottom part of which there is a shaft forming together with a nut interacting with it via the spline joint a clearance is considered.
S. A. Sergeev, M. N. Mikhaylova
doaj   +1 more source

Long‐Term Ambient Benzene Exposure and Brain Disorders Among Urban Adults: Effect Modification by Genetic Susceptibility and Potential Mediation by Plasma Proteins

Advanced Science, EarlyView.
Low‐level ambient benzene exposure is associated with increased risks of multiple brain disorders in urban adults. Genetic susceptibility modifies these associations, while plasma proteomics points to potential biological pathways linking benzene exposure to adverse brain health.
Jianhui Guo, Xia Zhong, Petros Koutrakis, Carolina L. Zilli Vieira, Feifei Si, Yaqi Wang, Xinyao Lian, Yi Fan, Zhaokun Wang, Shaodan Huang, Jing Li   +10 more
wiley   +1 more source

A Study on Two-Stage Cold Forging for a Drive Shaft with Internal Spline and Spur Gear Geometries

Metals, 2018
A two-stage cold forging process was proposed to manufacture a drive shaft with an internal spline and spur gear geometries, and this process was mainly composed of a forward extrusion for preform and a forward-backward extrusion for the drive shaft.
Tae-Wan Ku
doaj   +1 more source

Study on Internal Force of Tunnel Segment by Considering the Influence of Joints

Advances in Materials Science and Engineering, 2020
The mechanical performance of segments is an important aspect of the safety of tunnel structures. Study on the internal force of tunnel segment by considering the influence of joints is beneficial for obtaining a better understanding of the influence of ...
Linwei Dong, Zhiyong Yang, Zhenyong Wang, Yaowen Ding, Weiqiang Qi   +4 more
doaj   +1 more source

stMixer for Scalable Mosaic Integration and Label Transfer in Spatial Histology and Multi‐Omics

Advanced Science, EarlyView.
stMixer is an unsupervised framework for scalable integration and label transfer across spatial histology and multi‐slide multi‐omics data with incomplete modality overlap. It combines self‐looped cross‐attention, multimodal metric learning, and graph‐guided cluster voting to align heterogeneous sections, correct batch effects, and propagate ...
Qixing Yang, Yan Wang, Luonan Chen, Chunman Zuo   +3 more
wiley   +1 more source

Technique for the Determination of the Elastic Stiffness Coefficient of Interatomic Connection Based on the Experimental Weight-Loading Curve [PDF]

Журнал нано- та електронної фізики, 2012
Calculation technique of the elastic stiffness coefficient of interatomic binding and interatomic forces for the crystal lattice of the deformed body is presented.
K.D. Evfimko, A.A. Gaisha, A.A. Mochalov   +2 more
doaj  

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

Advanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan, Xuran Li, Han Wang, Lin Sun, Yao Wang, Jiangdong Wu, Junqi Cui, Yiqi Yang, Kai Yuan, Linyang Chu, Liao Wang, Hanjun Li, Mengning Yan, Zhifeng Yu   +13 more
wiley   +1 more source

Simulation and Experimental Study of Ultrasonic Vibratory Grinding of Internal Splines

Machines
As an important component of mechanical transmission systems, internal splines are widely used in aerospace, industrial equipment, and other fields. However, internal splines are prone to deformation and shrinkage after heat treatment.
Zemin Zhao, Shuangshuang Zhou, Qiang Liu, Long Zhang, Bin Shen, Jiaming Han   +5 more
doaj   +1 more source

An exciting Approach to Theoretical Spectroscopy

Advanced Science, EarlyView.
ABSTRACT Theoretical spectroscopy, and more generally, electronic‐structure theory, are powerful concepts for describing the complex many‐body interactions in materials. They cover methods from ground‐state properties to lattice excitations and light‐matter interaction, including time‐resolved variants.
Martí Raya‐Moreno, Alexander Buccheri, Noah Alexy Dasch, Nasrin Farahani, Ignacio Gonzalez Oliva, Andris Gulans, Seokhyun Hong, Manoar Hossain, Hannah Kleine, Martin Kuban, Sven Lubeck, Benedikt Maurer, Pasquale Pavone, Fabian Peschel, Daria Popova‐Gorelova, Lu Qiao, Elias Richter, Santiago Rigamonti, Ronaldo Rodrigues Pela, Maximilian Schebek, Kshitij Sinha, Daniel T. Speckhard, Jan Stutz, Sebastian Tillack, Dmitry Tumakov, Jānis Užulis, Mara Voiculescu, Cecilia Vona, Mao Yang, Claudia Draxl   +29 more
wiley   +1 more source