AxonDeepSeg: automatic axon and myelin segmentation from microscopy data using convolutional neural networks [PDF]
, 2017 Segmentation of axon and myelin from microscopy images of the nervous system provides useful quantitative information about the tissue microstructure, such as axon density and myelin thickness. This could be used for instance to document cell morphometry
Antonsanti, Pierre-Louis +5 more
core +3 more sources
A supervised clustering approach for fMRI-based inference of brain states [PDF]
, 2011 We propose a method that combines signals from many brain regions observed in functional Magnetic Resonance Imaging (fMRI) to predict the subject's behavior during a scanning session.
Alexandre Gramfort +40 more
core +5 more sources
Methods for computing the maximum performance of computational models of fMRI responses.
PLoS Computational Biology, 2019 Computational neuroimaging methods aim to predict brain responses (measured e.g. with functional magnetic resonance imaging [fMRI]) on the basis of stimulus features obtained through computational models.
Agustin Lage-Castellanos +3 more
doaj +1 more source
Mapping hybrid functional-structural connectivity traits in the human connectome [PDF]
, 2018 One of the crucial questions in neuroscience is how a rich functional repertoire of brain states relates to its underlying structural organization. How to study the associations between these structural and functional layers is an open problem that ...
Amico, Enrico, Goñi, Joaquín
core +2 more sources
Deep learning predictions of survival based on MRI in amyotrophic lateral sclerosis
NeuroImage: Clinical, 2017 Amyotrophic lateral sclerosis (ALS) is a progressive neuromuscular disease, with large variation in survival between patients. Currently, it remains rather difficult to predict survival based on clinical parameters alone. Here, we set out to use clinical
Hannelore K. van der Burgh +5 more
doaj +1 more source
His+ reversions Caused in Salmonella typhimurium by different types of ionizing radiation [PDF]
, 1988 The yield of his+ reversions in the Ames Salmonella tester strain TA2638 has been determined for 60Co γ rays, 140 kV X rays, 5.4 keV characteristic X rays, 2.2 MeV protons, 3.1 MeV α particles, and 18 MeV/U Fe ions.
Fitzek, M. +3 more
core +1 more source
Frontiers in Psychiatry, 2018 Background: Aquaporin 4 (AQP4) polymorphism may influence the required dosage of antipsychotic drugs. However, the roles of AQP4 polymorphisms in the blood—brain barrier (BBB) and different neuroprotective effects need further exploration.
Yung-Fu Wu +5 more
doaj +1 more source
Tissue-specific impact of stem-loops and quadruplexes on cancer breakpoints formation
BMC Cancer, 2019 Background Chromosomal rearrangements are the typical phenomena in cancer genomes causing gene disruptions and fusions, corruption of regulatory elements, damage to chromosome integrity. Among the factors contributing to genomic instability are non-B DNA
Kseniia Cheloshkina, Maria Poptsova
doaj +1 more source
Shell Neurons of the Master Circadian Clock Coordinate the Phase of Tissue Clocks Throughout the Brain and Body [PDF]
, 2015 Background: Daily rhythms in mammals are programmed by a master clock in the suprachiasmatic nucleus (SCN). The SCN contains two main compartments (shell and core), but the role of each region in system-level coordination remains ill defined.
Baba, Kenkichi +14 more
core +2 more sources
Voices in Bioethics, 2013 Science fiction is a ripe area for bioethical analysis. The consideration of how technology will impact lives in the future is of great concern to bioethicists, and the power of fiction can bring the energy of authentic human emotions and relationships ...
Sara Bergstresser
doaj +1 more source