Results 51 to 60 of about 1,938 (182)

Targeting Orexin 2 Receptors in Idiopathic Hypersomnia and Narcolepsy: A Randomised Phase 1b Proof‐Of‐Concept Study of Alixorexton

Journal of Sleep Research, EarlyView.
Orexin 2 receptor agonists have demonstrated that targeting the orexin system may address symptoms of central disorders of hypersomnolence. Results of this phase 1 study support the phase 2 clinical evaluation of oral alixorexton in patients with IH, NT2 and NT1.
Ronald R. Grunstein, Brendon J. Yee, Julia L. Chapman, Jian Eu Tai, Sheila Sivam, Craig Hopkinson, Daniel G. Smith, Alexandra Lovett, Shifang Liu, Sergey Yagoda, Bhaskar Rege   +10 more
wiley   +1 more source

Water-immersion softening mechanism of coal rock mass based on split Hopkinson pressure bar experiment

International Journal of Coal Science & Technology, 2022
The coal mining process is affected by various water sources such as groundwater and coal seam water injection. Understanding the dynamic mechanical parameters of water-immersed coal is helpful for coalmine safe production.
Zhiyuan Liu, Gang Wang, Jinzhou Li, Huaixing Li, Haifeng Zhao, Hongwei Shi, Jianli Lan   +6 more
doaj   +1 more source

Designing a Data Acquisition System for a Split Hopkinson Pressure Bar [PDF]

2015 ASEE Annual Conference and Exposition Proceedings, 2015
Designing a Data Acquisition System for a Split Hopkinson Pressure BarSenior students are always challenged to apply their engineering knowledge and research skillsgained from an engineering curriculum toward design and implementation of challenging seniordesign projects.
Sean Patrick Kirby, Julius Omokiniovo Ejenavi, Payam Matin   +2 more
openaire   +2 more sources

Spatial Variability and Drivers of Salt Marsh Cliff Erosion in the Dutch Wadden Sea: From Observation to Simulation

Journal of Geophysical Research: Earth Surface, Volume 131, Issue 8, August 2026.
Abstract Lateral erosion of salt marshes via cliff retreat is a primary cause of global marsh loss, driven by interactions between hydrodynamics, sediment, and vegetation. While previous studies show a linear relationship between wave power and cliff retreat, models based on this relationship are largely unvalidated for short‐term (sub‐yearly) and ...
S. Dzimballa, V. Kitsikoudis, P. W. J. M. Willemsen, E. O. Folmer, B. W. Borsje, I. Y. Georgiou, M. C. Bregman, D. C. M. Augustijn   +7 more
wiley   +1 more source

Signal Correction for the Split-Hopkinson Bar Testing of Soft Materials

Dynamics
The Split-Hopkinson pressure bar (SHPB) test is a commonly accepted experiment to investigate the material behavior under high strain rates. Due to the low impedance of soft materials, here, the test has to be performed with plastic bars instead of metal
Sören Bieler, Kerstin Weinberg
doaj   +1 more source

Shear Fault Formation in Granite Under High and Transient Co‐Seismic Strain Rates Unveiled by Ultra‐Fast X‐Ray Imaging

Geophysical Research Letters, Volume 53, Issue 14, 28 July 2026.
Abstract During an earthquake a dynamic rupture propagates, causing fractures and permanent damage that modify the mechanical properties of the fault and its surroundings. Reciprocally, the energy dissipated by the mechanical transformation of the fault rock has a direct feedback on the dynamics of the seismic rupture.
A. R. Vishnu, Mai‐Linh Doan, James Hollingsworth, Fabian Barras, Benoît Cordonnier, François Renard   +5 more
wiley   +1 more source

Paleomagnetic Constraints on the Separation of the Olongbuluke Block From the North China Block During the Late Cambrian–Middle Ordovician and Its Tectonic Significance

Geophysical Research Letters, Volume 53, Issue 13, 16 July 2026.
Abstract The collisional evolution of the micro‐blocks in the northeastern Tibetan Plateau is relatively well constrained. However, the reason why a fragment of the North China Block, the Olongbuluke Block, became separated from North China by the Central Qilian Block (a fragment of the South China Block) remains unclear.
Teng Wang, Yanan Zhou, Ruiyang Chai, Xin Cheng, Hanning Wu   +4 more
wiley   +1 more source

A NOTE ON DATA PROCESSING IN THE SPLIT HOPKINSON PRESSURE BAR TESTS [PDF]

Experimental Techniques, 1998
In this paper, a close-form relationship between the incident wave and the transmitted wave was deduced on the analysis of elastic wave propagation in SHPB tests for the elastic specimen. The relationship was applied to determine the time delay in data processing of SHPB tests in order to improve the accuracy of the measured stress-strain curve in the ...
Yuan, J., Takeda, N., Waas, Anthony M.
openaire   +2 more sources

Evaluating Energy Absorption Performance of Filled Lattice Structures

Advanced Engineering Materials, Volume 28, Issue 13, 8 July 2026.
Maximum stress must be considered to robustly evaluate energy absorber designs. This approach was applied to compare all types of absorbers in a single Ashby diagram and determine the utility of filling lattice voids with a second material. High‐performance fillers can improve the performance of lattices that are limited by buckling or catastrophic ...
Christian Bonney, William P. King, Iwona Jasiuk   +2 more
wiley   +1 more source

Dynamic tensile strength and fracture evolution of characteristic shale with bedding and hole using linear regression theory

Deep Underground Science and Engineering, Volume 5, Issue 2, Page 426-445, June 2026.
The spiral conical perforations generated during methane in situ explosion fracturing operations lead to tensile fracture propagation in shale reservoirs being governed by the combined effects of impact pressure, bedding, and aperture under explosive loading. Using multiple regression analysis and digital image correlation technology, the mechanisms of
Yabo Chai, Ning Luo, Jianan Zhou, Haohao Zhang, Penglong Li, Yu Wang, Cheng Zhai, Tianran Ma   +7 more
wiley   +1 more source