Results 151 to 160 of about 641,965 (315)

Referee report. For: Study protocol for a cluster-randomized split-plot design trial to assess the effectiveness of targeted active malaria case detection among high-risk populations in Southern Lao PDR (the AcME-Lao study) [version 1; peer review: 3 approved]

, 2020
Kamala Thriemer
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Produtividade e composição bromatológica de Brachiaria spp., no Alto Vale do Jequitinhonha Productivity and bromatological composition of Brachiaria spp. in the Higher Jequitinhonha Valley

Ciência e Agrotecnologia, 2011
Avaliaram-se a produtividade de matéria seca (MS), proporção de lâminas e composição bromatológica de Brachiaria spp., colhidas com 42 dias de rebrotação, em Diamantina, MG.
Rosana Cristina Pereira, Karina Guimarães Ribeiro, Odilon Gomes Pereira, Janaina de Lima Silva, Jakline Magela dos Santos, João Paulo Sampaio Rigueira   +5 more
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Python script of split-plot design analysis with block permutations

L. A. Bermejo
openalex   +1 more source

Using Model of Split-Plot Design in the Study of Factors Affecting on Accepted in Stock Exchange Agricultural Machinery Companies Liquidity

, 2015
Vahide Hajihassani, Yadollah Rajaei
openalex   +1 more source

Balancing Multiple Criteria Incorporating Cost using Pareto Front Optimization for Split‐Plot Designed Experiments [PDF]

, 2012
Lu Lu, Christine M. Anderson‐Cook
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

D-optimal design of split-split-plot experiments

, 2009
Bradley Jones, Peter Goos
openalex   +2 more sources