ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi +8 more
wiley +1 more source
From Spreadsheet To Prediction Tool: A Practical Artificial Intelligence Guide For Urologists. [PDF]
Joshi A +7 more
europepmc +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Low-Cost Non-Invasive Microwave Glucose Sensor Based on Dual Complementary Split-Ring Resonator. [PDF]
Xu G, Kang Z, Feng X, Li M.
europepmc +1 more source
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon +11 more
wiley +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Middle Meatal Spacers for Synechiae Prevention Following Endoscopic Sinus Surgery: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]
Chowdhury R +6 more
europepmc +1 more source
Explainable Bidirectional Long Short-Term Memory Networks Learn Chemistry from SMILES for Predicting Toxicity of Androgen and Estrogen Receptor Chemicals. [PDF]
Cutropia F +11 more
europepmc +1 more source
Effects of a Greek Yoghurt-based Complex on the Human Facial Skin Microbiome. [PDF]
Voyiatzis I +8 more
europepmc +1 more source
Interactions Between Donor and Recipient age in Liver Transplantation: Implications for Donor and Recipient Matching. [PDF]
Elias C +11 more
europepmc +1 more source

