Results 31 to 40 of about 816 (250)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Experimental study of compressor electric current detection for a split-type air conditioner affects energy savings

International Journal of Electrical and Computer Engineering (IJECE), 2023
The paper presents an experimental study that aims to measure the compressor electric current of a split-type air conditioner for analyzing the various abnormal condition of the R-32 refrigerant pressure, especially for detecting compressor electric current while occurring dirt in the evaporator coil and condenser coil. The method was to install sensor
Banjerd Saengchandr, Viroch Sukontanakarn, Kriangkrai Waiyagan   +2 more
openaire   +2 more sources

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Numerical Study of an Ejector as an Expansion Device in Split-type Air Conditioners for Energy Savings [PDF]

Journal of Engineering and Technological Sciences, 2013
The present study describes a numerical approach for determining both the motive nozzle and constant-area diameters of an ejector as an expansion device, based on the cooling capacity of a split-type air-conditioner using R290 as refrigerant. Previous studies have shown that replacement of HCFC R22 with HC290 (propane) in the air conditioner can ...
Kasni Sumeru, Shodiya Sulaimon, Farid Nasir Ani, Henry Nasution   +3 more
openaire   +1 more source

Small photovoltaic setup for the air conditioning system

E3S Web of Conferences, 2017
The increasing interest in air conditioning systems for residential applications in Poland will certainly increase the demand for electricity during the summer period.
Masiukiewicz Maciej
doaj   +1 more source

Room air conditioning performance using liquid-suction heat exchanger retrofitted with R290

Case Studies in Thermal Engineering, 2019
In this paper, a study of room air conditioning performance when using a liquid-suction heat exchanger retrofitted with R290 has been carried out with the aim of determining the influence of LSHX and R290 in terms of refrigeration effect, power ...
Dian Morfi Nasution, Muhammad Idris, Nugroho Agung Pambudi, Weriono   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Research of parameters of the air environment indoors with the conditioner split-system

RUDN Journal of Engineering Research, 2011
Researches of parametres of the air environment indoors for the purpose of definition of influence of the conditioner of type Split-system on air exchange are conducted.
A N Malov, Y V Nikolenko, N A Stashevskaya   +2 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source