Split Reporter Systems in Viral Protein-Protein Interactions and Multimerization: Mechanisms and Applications. [PDF]
Ahmad H +5 more
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
High-frequency Plunger Lift Process for Deep Shale Gas Wells
In the Weirong gas field, as the horizontal well exploitation of deep shale gas enters to the mid-late stage with high water production and huge liquid loading in deviated sections, conventional plunger lift processes cannot satisfy the requirements of ...
Liu Tong +4 more
doaj
U-SplitDoRA: an improved privacy-preserved U-shaped split parameter-efficient fine-tuning framework through weight decomposition for large language models. [PDF]
Singh S +3 more
europepmc +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Shifting Balancing Selection Underlies an Inversion Cline in Eurasian Blackcap. [PDF]
Ishigohoka J, Liedvogel M.
europepmc +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Split hamate fractures as part of complex ulnar carpometacarpal injuries: radiographic and functional outcomes. [PDF]
Glaser J +5 more
europepmc +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Outcomes of Internal Fixation in Proximal Humerus Head Split Fractures in Young Adults - How Often Is It Missed and Can We Really Afford to Do So. [PDF]
Mukherjee K +3 more
europepmc +1 more source

