Results 131 to 140 of about 1,126,210 (312)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
DRUŠTVENO ODGOVORNO POSLOVANJE NA PRIMJERU STUDENTSKOG CENTRA SPLIT : Završni rad [PDF]
, 2018 U radu je teorijski obrađeno društveno odgovorno poslovanje u Studentskom centru Split te kako se isto odražava na zadovoljstvo zaposlenika, zatim je u empirijskom dijelu rada anketiranjem ispitano zadovoljstvo zaposlenika u Studentskom centru Split ...
Kolić, Ivana
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
U ovom radu analiza je bila usmjeren ka destinaciji Split, odnosno njenim istaknutim privlačnim faktorima turističke potražnje kao i utjecaju COVID-19 pandemije na destinaciju Split.
Bulat, Antonija
core +1 more source
Splits - ineficiência no mercado de ações
RAE: Revista de Administração de Empresas, 1994 Uma pesquisa empírica investiga, na Bolsa de Valores de São Paulo, a existência de imperfeições de mercado associadas a splits.
Jaci Corrêa Leite
doaj
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Strategic Approach for Enhancing Deep Learning Models
AlgorithmsModern large language models have achieved remarkable growth and performance across domains, yet their intense use of resources and high computational costs present challenges to scalability and sustainability. Current attempts to surpass baseline (naïve)
Oded Koren +2 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source