Results 41 to 50 of about 94,998 (262)
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Large Graph Sampling Algorithm for Frequent Subgraph Mining
IEEE Access, 2021 Large graph networks frequently appear in the latest applications. Their graph structures are very large, and the interaction among the vertices makes it difficult to split the structures into separate multiple structures, thus increasing the difficulty ...
Tianyu Zheng, Li Wang
doaj +1 more source
Molecular Oncology, EarlyView.Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Computing Minimum Rainbow and Strong Rainbow Colorings of Block Graphs [PDF]
Discrete Mathematics & Theoretical Computer Science, 2018 A path in an edge-colored graph $G$ is rainbow if no two edges of it are colored the same. The graph $G$ is rainbow-connected if there is a rainbow path between every pair of vertices.
Melissa Keranen, Juho Lauri
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Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Discrete Mathematics & Theoretical Computer Science, 2007 An undirected graph G=(V,E) is a probe split graph if its vertex set can be partitioned into two sets, N (non-probes) and P (probes) where N is independent and there exists E' ⊆ N× N such that G'=(V,E∪ E') is a split graph. Recently Chang et al.
Van Bang Le, H.N. de Ridder
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Informatika, 2018 A hypergraph is called k-chromatic if its vertex set can be partitioned into at most k pairwise disjoint subsets when each subset has no more than two common vertices with every edge of the hypergraph.
T. V. Lubasheva
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