Results 221 to 230 of about 963,610 (298)

Water and nitrogen management strategies influence grain filling and yield of winter wheat in the North China Plain. [PDF]

Front Plant Sci
Cao Z, Gao G, Duan Y, Zhang H, Tian C, Zhao C, Xu X.   +6 more
europepmc   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

A Real-Time Antifouling Multivalent Aptamer Platform for Wash-Free Electrochemical Detection of Low-Abundance Biomarkers in Human Plasma. [PDF]

Angew Chem Int Ed Engl
Sen P, Saxena S, Zhang Z, Sandhu N, Das P, Gu J, Hoare T, Li Y, Soleymani L.   +8 more
europepmc   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Integrating trajectory inference and self-explainable predictive models to explore cell state transitions in breast cancer at single-cell resolution. [PDF]

Front Bioinform
Verrina V, Talia M, Cesario E, Capalbo S, Scordamaglia D, Lappano R, Miglietta AM, Maggiolini M, Giordano S.   +8 more
europepmc   +1 more source

Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann, Theresa Lüth, Susen Schaake, Carolin Gabbert, Marius Möller, Hauke Busch, Katja Lohmann, Jonas A. Gustafson, Danny E. Miller, Kensuke Daida, Manabu Funayama, Nobutaka Hattori, Samia Ben Sassi, Faycel Hentati, Matthew J. Farrer, Kristian K. Ullrich, Christine Klein, Joanne Trinh   +17 more
wiley   +1 more source

Dynamic neutrophil-keratinocyte communication network centered on IL-36/TNFSF15 responses characterizes inflammatory responses in generalized pustular psoriasis. [PDF]

Nat Commun
Jiang R, Kirma J, Fox J, Xing X, Wang J, Sarkar MK, Bogle R, Do T, Coon A, Cole C, Plazyo O, Rew JE, Zhang H, Kahlenberg JM, Billi AC, Bachelez H, Tsoi LC, Harms PW, Shao S, Chen X, Gudjonsson JE.   +20 more
europepmc   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Single-Cell Profiling Reveals RAB13⁺ Endothelial Cells and Profibrotic Mesenchymal Cells in Aged Human Bone Marrow. [PDF]

Aging Cell
Cenzano I, Cócera M, Lopez-Perez AR, Campos-Dopazo L, Ruiz J, Sancho I, Martin-Uriz PS, Aguirre-Ruiz P, Sarvide S, Vilas-Zornoza A, Ripalda-Cemborain P, Alignani D, Lopez A, Barrios MM, Agreda DQ, Ye J, Lehmann R, Sudupe L, Abengozar-Muela M, Lopez-Janeiro Á, Tamariz-Amador LE, Muiños-López E, Saez B, Tegner J, Calvo IA, Gomez-Cabrero D, Prosper F.   +26 more
europepmc   +1 more source

Classification of Cochrane Plain Language Summaries by Conclusiveness Using Transformer-Based Models and ChatGPT: Retrospective Observational Study.

JMIR Med Inform
Mijatović A, Ursić L, Bralić N, Bandić R, Ćaćić B, Buljan I, Marušić A.   +6 more
europepmc   +1 more source