Results 41 to 50 of about 221,778 (302)

Optimal Designs For the Restricted Maximum Likelihood Estimators in a Random Split-Plot Model

open access: yesLithuanian Journal of Statistics, 2017
The design effect for the restricted maximum likelihood estimators of variance components in acompletely randomized split-plot model is studied. The model was used to represent the response generated froman experimental scenario where the whole-plot and
Oluwole Nuga, G. N. Amahia, Fatai Salami
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Effects of Process Parameters in the Production of High Density Polyethylene-Grass Composite

open access: yesJournal of Applied Sciences and Environmental Management, 2018
This study investigates the effects of process parameters in the production of high density polyethylene-grass composite; the process parameters and their interaction on the mechanical properties of the produced high density polyethylene-grass composite
DD Olodu, JO Osarenmwinda
doaj   +1 more source

Split-plot designs for multistage experimentation [PDF]

open access: yesJournal of Applied Statistics, 2016
ABSTRACTMost of today’s complex systems and processes involve several stages through which input or the raw material has to go before the final product is obtained. Also in many cases factors at different stages interact. Therefore, a holistic approach for experimentation that considers all stages at the same time will be more efficient. However, there
Tyssedal, John Sølve, Kulahci, Murat
openaire   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The Effect of Vermicompost and PGPR on Physiological Traits of Lemon Balm (Melissa officinalis L.) Plant under Drought Stress [PDF]

open access: yesJournal of Medicinal Plants and By-products, 2016
In this research, effect of vermicompost and plant growth promoting rhizobacteria (PGPR) on physiological traits of lemon balm under drought stress condition was investigated in year 2012 at Karaj Research Institute of Forest and Rangelands.
Abolfazl Kazeminasab   +4 more
doaj  

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

D-OPTIMAL DESIGNS FOR SPLIT-PLOT MIXTURE PROCESS VARIABLE DESIGNS OF THE STEEL SLAG EXPERIMENT

open access: yesBarekeng, 2022
The nature of the steel slag concrete experiment followed a mixture process variable (MPV) design. In this study, the concrete is composed of five mixture components, cement, fine aggregate, coarse aggregate, percentage steel slag replaced the fine ...
Faula Arina   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

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