Results 31 to 40 of about 9,570 (204)
, 1995 In this paper we consider a special class of arithmetic quotients of bounded symmetric domains which can roughly be described as higher- dimensional analogues of the Hilbert modular varities.
Hunt, Bruce
core +2 more sources
Octonion Quantum Chromodynamics
, 2012 Starting with the usual definitions of octonions, an attempt has been made to establish the relations between octonion basis elements and Gell-Mann \lambda matrices of SU(3)symmetry on comparing the multiplication tables for Gell-Mann \lambda matrices of
A. Cayley +32 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Computing automorphic forms on Shimura curves over fields with arbitrary class number
, 2010 We extend methods of Greenberg and the author to compute in the cohomology of a Shimura curve defined over a totally real field with arbitrary class number.
H. Hida +11 more
core +3 more sources
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
, 2016 Let $-d$ be a a negative discriminant and let $T$ vary over a set of representatives of the integral equivalence classes of integral binary quadratic forms of discriminant $-d$.
A Earnest +24 more
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
The conic-gearing image of a complex number and a spinor-born surface geometry
, 2011 Quaternion (Q-) mathematics formally contains many fragments of physical laws; in particular, the Hamiltonian for the Pauli equation automatically emerges in a space with Q-metric.
A. P. Yefremov +7 more
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The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source