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Comparison of in silico predicted Mycobacterium tuberculosis spoligotypes and lineages from whole genome sequencing data [PDF]
Bacterial strain-types in the Mycobacterium tuberculosis complex underlie tuberculosis disease, and have been associated with drug resistance, transmissibility, virulence, and host–pathogen interactions.
Gary Napier+8 more
doaj +2 more sources
Spoligotypes of Mycobacterium tuberculosis from Different Provinces of China [PDF]
ABSTRACT A total of 2,346 Mycobacterium tuberculosis isolates from 13 provinces in China were genotyped by spoligotyping. Two hundred seventy-eight spoligotypes were identified: 2,153 isolates were grouped into 85 clusters, and the remaining 193 isolates were orphans. Comparison with the SpolDB4.0 database
Jie Liu+7 more
openaire +3 more sources
Mapping of Mycobacterium tuberculosis Complex Genetic Diversity Profiles in Tanzania and Other African Countries [PDF]
The aim of this study was to assess and characterize Mycobacterium tuberculosis complex (MTBC) genotypic diversity in Tanzania, as well as in neighbouring East and other several African countries.
A Ignatova+78 more
core +33 more sources
To tackle the spread of tuberculosis (TB), epidemiological studies are undertaken worldwide to investigate TB transmission chains. Clustered regulatory interspaced short palindromic repeats (CRISPR) locus diversity, also called spoligotyping, is a widely
Charlotte Genestet+7 more
doaj +1 more source
Diagnosis of tuberculosis in pediatric patients remains challenging due to inherent difficulties associated with obtaining respiratory samples for molecular and culture-based testing. To address this, recent studies have highlighted the utility of tongue
Christopher Ealand+13 more
doaj +1 more source
Global Distribution of Mycobacterium tuberculosis Spoligotypes [PDF]
Nous présentons un bref résumé des observations récentes sur la distribution mondiale des principaux clades du complexe Mycobacterium tuberculosis, l'agent causal de la tuberculose. Cette distribution globale a été définie par l'exploration de données d'une base de données internationale de spoligotypage, SpolDB3.
Ingrid Filliol+48 more
openaire +6 more sources
Typing of mycobacteria using spoligotyping [PDF]
The potential use of spoligotyping—a polymerase chain reaction based typing system for differentiation of strains of Mycobacterium tuberculosis —for studying the epidemiology of tuberculosis in developing countries which do not routinely perform mycobacterial culture is described in this issue of Thorax by Heyderman et al in a study from Zimbabwe.1 How
Andrew Hayward, James E. M. Watson
openaire +2 more sources
Rapid and accurate detection of tuberculosis (TB) drug resistance is critical for the successful treatment and control of TB. Here, we investigated resistance to anti-TB drugs and genetic variations in 215 drug-resistant Mycobacterium tuberculosis ...
Se-Mi Jeon+6 more
doaj +1 more source
Validation of a Microbead-Based Format for Spoligotyping of Legionella pneumophila [PDF]
ABSTRACT A 42-plex clustered regularly interspaced short palindromic repeat (CRISPR)-based typing technique (spoligotyping) was recently developed at the French National Reference Center for Legionella .
Gomgnimbou, Michel Kiréopori+7 more
openaire +7 more sources
Spoligotype Variation of Mycobacterium tuberculosis Strains Prevailing in Korea [PDF]
Tuberculosis (TB) is an ongoing global health problem, including in South Korea. To manage TB efficiently, it is necessary to understand the epidemiology, transmission route, and characteristics of prevailing Mycobacterium tuberculosis strains. In this study, we investigated microevolutions over time in the spoligotype patterns of M.
Seung-Eun Song+5 more
openaire +4 more sources