Use of Spoligotyping for Accurate Classification of Recurrent Tuberculosis [PDF]
Journal of Clinical Microbiology, 2002 ABSTRACT The spoligotyping method has become an important tool for the tracking of Mycobacterium tuberculosis strains in different epidemiological settings. In this study, we demonstrate the ability of the spoligotyping technique to accurately determine the pathogenetic mechanism of recurrent disease. This
Warren R.M. +7 more
openaire +3 more sources
Memorias do Instituto Oswaldo Cruz, 2011 The aim of the present study was to compare polymerase chain reaction (PCR)-based methods - spoligotyping and mycobacterial interspersed repetitive units (MIRU) typing - with the gold-standard IS6110 restriction fragment length polymorphism (RFLP ...
Mandira Varma-Basil +8 more
doaj +1 more source
Detecting Mutations in the Mycobacterium tuberculosis Pyrazinamidase Gene pncA to Improve Infection Control and Decrease Drug Resistance Rates in Human Immunodeficiency Virus Coinfection. [PDF]
, 2016 Hospital infection control measures are crucial to tuberculosis (TB) control strategies within settings caring for human immunodeficiency virus (HIV)-positive patients, as these patients are at heightened risk of developing TB.
Bangsberg +41 more
core +2 more sources
Tuberculosis in Poland: Epidemiological and Molecular Analysis during the COVID-19 Pandemic
Diagnostics, 2022 The COVID-19 pandemic may have a negative impact on the proper implementation of TB control programmes and may increase TB incidence rates in the near future. The aim of this study was to perform an epidemiological and molecular analysis of Mycobacterium
Dagmara Borkowska-Tatar +3 more
doaj +1 more source
Molecular epidemiological monitoring of the tuberculosis pathogen in the Arkhangelsk region
Журнал микробиологии, эпидемиологии и иммунобиологии, 2023 Introduction. Against the background of improvement of the main epidemiological indicators (morbidity and mortality) for tuberculosis in the Arkhangelsk region, the proportion of newly diagnosed tuberculosis patients with multidrug-resistant pathogen ...
Аnna А. Vyazovaya +7 more
doaj +1 more source
Molecular-genetic analysis of Mycobacterium tuberculosis strains spread in different patient groups in St.Petersburg (Russia) [PDF]
, 2011 Molecular epidemiological features of M.tuberculosis strains spread among different patient groups in Russia is not studied well. The aim of our study was to compare genotypes of M.tuberculosis strains circulating among TB patients from different groups:
Andrei Kozlov +5 more
core +3 more sources
Frontiers in Veterinary Science, 2021 Molecular diagnosis of bovine tuberculosis plays an essential role in the epidemiological knowledge of the disease. Bovine tuberculosis caused by Mycobacterium bovis represents a risk to human health.
Elizabeth Hortêncio de Melo +10 more
doaj +1 more source
A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis. [PDF]
, 2017 Pyrazinamide (PZA) is an important first-line drug in all existing and new tuberculosis (TB) treatment regimens. PZA-resistance in M. tuberculosis is increasing, especially among M/XDR cases.
Catanzaro, A +7 more
core +1 more source
embCAB Sequence Variation Among Ethambutol-Resistant Mycobacterium Tuberculosis Isolates Without embB306 Mutation [PDF]
, 2010 Mechanisms of resistance to ethambutol in Mycobacterium tuberculosis remain inadequately described. Although there is mounting evidence that mutations of codon 306 in embB play a key role, a significant number of phenotypically ethambutol-resistant ...
Ahmad +27 more
core +2 more sources
Molecular epidemiology of Mycobacterium africanum in Ghana [PDF]
, 2016 BACKGROUND: Mycobacterium africanum comprises two phylogenetic lineages within the M. tuberculosis complex (MTBC) and is an important cause of human tuberculosis (TB) in West Africa. The reasons for this geographic restriction of M.
Ahorlu, Collins +13 more
core +2 more sources