Results 11 to 20 of about 3,684 (214)

Expanding the Genetic Framework: Insights into Non-HLA-B27 Contributions to Axial Spondylarthritis [PDF]

Medicina (Lithuania)
Background and Objectives: Spondylarthritis is a complex group of inflammatory diseases closely associated with the HLA-B27 antigen. However, the role of non-HLA-B27 alleles in the disease’s pathogenesis has gained significant scholarly attention in ...
Ruxandra-Elena Nagiţ, Ioana Bratoiu, Mariana Pavel   +2 more
exaly   +5 more sources

Development and implementation of the international AIDA network spondylarthritis registry [PDF]

Frontiers in Medicine
During the last decade, spondyloarthritis (SpA) has increasingly been considered a disease at the crossroads between autoimmunity and autoinflammation.
Valeria Caggiano, Patrizia Barone, Perla Ayumi Kawakami-Campos   +2 more
exaly   +4 more sources

Exploring the Pathogenesis of Spondylarthritis beyond HLA-B27: A Descriptive Review [PDF]

International Journal of Molecular Sciences
Spondylarthritis (SpA) is a chronic inflammatory condition that encompasses damage to the axial or peripheral skeleton, accompanied by specific extra-articular symptoms.
Ruxandra-Elena Nagiţ, Elena Rezus, Petru Cianga   +2 more
exaly   +3 more sources

MRI Findings in Axial Psoriatic Spondylarthritis

Diagnostics, 2023
Psoriatic arthritis is a significant medical condition with a high prevalence, a wide variety of non-specific symptoms, and a high degree of overlap with other spondylarthritis disorders, particularly ankylosing spondylitis.
Loredana Sabina Pascu, Nicolae Sârbu, Andrei Vlad Brădeanu, Daniela Jicman (Stan), Madalina Nicoleta Matei, Mihaela Ionela Sârbu, Doina Carina Voinescu, Aurel Nechita, Alin Laurențiu Tatu   +8 more
doaj   +2 more sources

Metabolomics in spondylarthritis

BMC Rheumatology
Background and aim Spondyloarthritides (SpA) are common entities of the inflammatory rheumatic type. There are still 3 relevant problems in everyday clinical practice: early disease detection, cardiovascular risk assessment, and less so, disease activity
Susann Patschan, Constantin Remus, Inga Claus, Meike Hoffmeister, Oliver Ritter, Daniel Patschan   +5 more
doaj   +3 more sources

Role of NOD2 variants in spondylarthritis [PDF]

Arthritis & Rheumatism, 2002
AbstractObjectiveTo investigate the role of the gene NOD2 in susceptibility to, and clinical manifestations of, ankylosing spondylitis (AS).MethodsA case–control study of NOD2 polymorphisms known to be associated with Crohn's disease (CD) (Pro268Ser, Arg702Trp, Gly908Arg, and Leu1007fsinsC) was performed in 229 cases of primary AS with no diagnosed ...
Crane, A.M., Bradbury, L.A., Van Heel, D.A., McGovern, D.P.B., Brophy, S., Rubin, L., Siminovitch, K.A., Wordsworth, B.P., Calin, A., Brown, M.A.   +9 more
openaire   +8 more sources

Innovative Therapie der juvenilen Spondylarthritis – Enthesitis-assoziierte Arthritis

Kinder- Und Jugendmedizin, 2015
ZusammenfassungJuvenile Spondylarthritis steht für Erkrankungen, die u. a. die JIA-Kategorie der Enthesitisassoziierten Arthritis (EEA) und die juvenile ankylosiernde Spondylitis einschließen.
Gerd Horneff
exaly   +2 more sources

Spondylarthritis in the absence of B lymphocytes [PDF]

Arthritis & Rheumatism, 2008
AbstractThe highly effective treatment of rheumatoid arthritis by B cell depletion and the presence of B cells in the peripheral and axial lesions of patients with spondylarthritis (SpA) raise the question as to whether B lymphocytes could also be an appropriate therapeutic target in the latter disease.
Baeten, Dominique, Kruithof, Elli, Breban, Maxime, Tak, Paul P.   +3 more
openaire   +4 more sources

Real world efficacy safety and drug survival of secukinumab over 6 years at the largest biological center in Poland [PDF]

Scientific Reports
Advances in biologic and targeted synthetic DMARDs have expanded treatment options for spondylarthritis. Despite improvements with TNF inhibitors, many patients remain refractory.
Anna Felis-Giemza, Małgorzata Stasiek, Karolina Palej, Marta Wysmołek-Sołtysik, Marta Łosoś, Sandra Stańczyk, Joanna Werońska-Tatara, Jakub Wroński   +7 more
doaj   +2 more sources

Imaging and Interpretation of Axial Spondylarthritis: The Radiologist's Perspective—Consensus of the Arthritis Subcommittee of the ESSR

Seminars in Musculoskeletal Radiology, 2014
This article reflects the radiologist's perspective on the imaging and interpretation of axial spondylarthritis (SpA). The arthritis subcommittee of the European Society of Skeletal Radiology provides a consensus for the following questions: When and how
Vasco V Mascarenhas, Andrea Klauser, Lennart Jans   +2 more
exaly   +2 more sources