Results 11 to 20 of about 2,415 (182)

Tumor necrosis factor inhibitors are associated with reduced complement activation in spondylarthropathies: An observational study. [PDF]

PLoS ONE, 2019
BackgroundThe complement system is involved in pathogenesis of cardiovascular disease, and might play a role in accelerated atherogenesis in spondylarthropathies (SpA).
Ingrid Hokstad, Gia Deyab, Morten Wang Fagerland, Torstein Lyberg, Gunnbjørg Hjeltnes, Øystein Førre, Stefan Agewall, Tom Eirik Mollnes, Ivana Hollan   +8 more
doaj   +3 more sources

Clinical Impact of HLA‐B27 on Juvenile Idiopathic Arthritis: Eighteen Years of Follow‐up in the Population‐Based Nordic Juvenile Idiopathic Arthritis Cohort [PDF]

ACR Open Rheumatology
Objective We have previously shown that HLA‐B27 was negatively associated with remission status eight years after the onset of juvenile idiopathic arthritis (JIA).
Maria Ekelund, Agnes Szentpetery, Ellen D. Arnstad, Kristiina Aalto, Anders Fasth, Mia Glerup, Troels Herlin, Charlotte Myrup, Ellen Nordal, Suvi Peltoniemi, Marite Rygg, Veronika Rypdal, Lillemor Berntson   +12 more
doaj   +3 more sources

Effects of Antirheumatic Treatment on Cell Cholesterol Efflux and Loading Capacity of Serum Lipoproteins in Spondylarthropathies. [PDF]

J Clin Med, 2022
Spondyloarthropathies (SpA) are associated with increased cardiovascular risk. Among possible mechanisms is the dysfunction of serum lipoproteins in regulating cell cholesterol homeostasis.
Hokstad I, Greco D, Deyab G, Fagerland MW, Agewall S, Hjeltnes G, Zimetti F, Bernini F, Ronda N, Hollan I.   +9 more
europepmc   +2 more sources

Impact of disease outcomes on the Assessment of SpondyloArthritis International Society Health Index (ASAS HI): a Bayesian network analysis of the DESIR cohort [PDF]

RMD Open, 2023
Objective The objective of this study is to build a structural model visualising and quantifying the interrelationships of different disease outcomes with the Assessment of SpondyloArthritis International Society Health Index (ASAS HI) in patients with ...
Sofia Ramiro, Robert Landewé, Désirée van der Heijde, Maxime Dougados, Annelies Boonen, Jürgen Braun, Uta Kiltz, Imke Redeker   +7 more
doaj   +2 more sources

Ten-year follow-up of degenerative spinal lesions on radiographs and MRI in axial spondyloarthritis: results of the DESIR (DEvenir des spondylarthropathies indifférenciées récentes) cohort. [PDF]

Eur Radiol
To investigate the occurrence of spinal degenerative lesions (DL)s in axial spondyloarthritis (axSpA) inception cohort in radiographs and MRI over 10 years (10Y), to assess their changes over time and factors associated with them.
Pina Vegas L, van Lunteren M, Loeuille D, Morizot C, Newsum E, Ramiro S, van Gaalen F, Saraux A, Claudepierre P, Feydy A, van der Heijde D, Reijnierse M.   +11 more
europepmc   +2 more sources

Humoral and Cellular Immunogenicity and Safety of Five Different SARS-CoV-2 Vaccines in Patients With Autoimmune Rheumatic and Musculoskeletal Diseases in Remission or With Low Disease Activity and in Healthy Controls: A Single Center Study [PDF]

Frontiers in Immunology, 2022
BackgroundVaccine-induced immunity is essential for controlling the COVID-19 pandemic. Data on humoral and cellular immunogenicity and safety of different SARS-CoV-2 vaccines in patients with autoimmune rheumatic and musculoskeletal diseases (RMDs) are ...
Gábor J. Szebeni, Gábor J. Szebeni, Gábor J. Szebeni, Nikolett Gémes, Nikolett Gémes, Dániel Honfi, Enikő Szabó, Patrícia Neuperger, Patrícia Neuperger, József Á. Balog, József Á. Balog, Lajos I. Nagy, Zoltán Szekanecz, László G. Puskás, László G. Puskás, Gergely Toldi, Attila Balog   +16 more
doaj   +2 more sources

Different disease activity trajectories in early axial spondyloarthritis lead to significantly different long-term outcomes: a trajectory-based analysis of the DESIR cohort over 10 years [PDF]

RMD Open
Introduction The study aimed to identify and describe disease activity trajectories over 10 years in patients with recent-onset axial spondyloarthritis (axSpA) and determine their impact on long-term outcomes.Methods This prospective, multicentre study ...
Maxime Dougados, Laure Gossec, Anna Molto, Matthieu Resche-Rigon, Elodie Portier, Leslie Benattar   +5 more
doaj   +2 more sources

Association between sarcopenia and physical activity in individuals with spondyloarthritis [PDF]

Journal of Rheumatic Diseases
Objective: To assess the association between sarcopenia and physical activity in individuals with spondyloarthritis (SpA). Methods: Physical functional performance of individuals with SpA (SpA group [SG]: n=29, 10 males, mean age=50.6±10.2 years) and a ...
Bruna Oliveira Corrêa do Amaral, Christianne de Faria Coelho-Ravagnani, Ana Beatriz Silva de Vasconcelos, Silvio Assis de Oliveira-Junior, Paula Felippe Martinez   +4 more
doaj   +2 more sources

Trends in medications for autoimmune disorders during pregnancy and factors for their discontinuation: a population-based study [PDF]

BMC Pregnancy and Childbirth
Objectives The medications used for autoimmune diseases have significantly evolved in recent years, but there is limited knowledge about how treatment practices changed during pregnancy.
Sabine Mainbourg, Odile Sheehy, Jessica Gorgui, Evelyne Vinet, Anick Bérard   +4 more
doaj   +2 more sources

Certolizumab Pegol Reduced Anterior Uveitis Flares Compared With Standard Non-Biologic Treatment: Results From an Overlap Weighting Analysis in High-Risk Patients With Axial Spondyloarthritis. [PDF]

Int J Rheum Dis
ABSTRACT Objective Acute anterior uveitis (AAU) is the most common extra‐musculoskeletal manifestation of axial spondyloarthritis (axSpA). This study compared the effect of the tumor necrosis factor inhibitor (TNFi) certolizumab pegol (CZP) with standard non‐biologic care, on AAU flare rate in patients with axSpA and high risk of recurrent uveitis ...
Haroon N, Baskurt Z, Chim T, Inman RD, Kumke T, Tham R, Kim M, van der Horst-Bruinsma I, Gensler LS.   +8 more
europepmc   +2 more sources