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Decoding eQTLs: unraveling their role in spondyloarthropathies pathogenesis and potential therapeutics [PDF]
Expression quantitative trait loci (eQTLs) represent genetic variants that influence gene expression, providing insights into the mechanisms linking genetic predisposition to complex diseases, including spondyloarthropathies (SpAs).
Nabaa Ihsan Awadh +6 more
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Serum levels of tumor necrosis factor-like cytokine 1A and its receptors, death receptor 3 and decoy receptor 3, in patients with spondyloarthropathies: preliminary results from a cross-sectional study [PDF]
Introduction Tumor necrosis factor (TNF)-like cytokine 1A (TL1A) is a member of the TNF superfamily of cytokines, involved in regulation of the immune and inflammatory response. Recently, therapies aimed at blockade of the TL1A pathway have shown benefit
Emilia Anna Frąckiel +6 more
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High intensity interval training (HIIT) has been shown to benefit patients with psoriatic arthritis (PsA). However, magnetic resonance (MR) imaging has uncovered bone marrow edema (BME) in healthy volunteers after vigorous exercise.
Ioanna Chronaiou +7 more
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EQTL analyses are a formidable tool to define the immunogenetic mechanisms underpinning Spondyloarthropathies [PDF]
Matteo Vecellio +3 more
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IntroductionDysbiosis is an environmental factor that affects the induction of axial spondyloarthritis (axSpA) pathogenesis. In the present study, we investigated differences in the gut microbiota of patients with axSpA and revealed an association ...
Hong Ki Min +33 more
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Uveitis in spondyloarthropathies: Current concepts
Uveitis is the inflammation of the middle layer of the eye, the Uvea. Spondyloarthropathies are systemic disorders with common clinical and pathological features. Uveitis is an important and frequent extraarticular manifestation of spondyloarthropathies.
Krati Chauhan
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Introduction Spondyloarthropathies are a group of chronic inflammatory diseases with specific clinical symptoms in rheumatic diseases. These patients suffer from pain in the joints.
Elham Rajaei +4 more
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BackgroundSpondyloarthritis (SpA) are the most common group of chronic inflammatory rheumatic diseases affecting about 1.5% of the adult Caucasian population. Low back pain is the most common symptom.
Isabel Pimenta +20 more
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The spondyloarthropathies are a group of related conditions which have in common genetic factors, clinical features and a specific pathological target: the enthesis.
Sébastien Villotte, Sacha Kacki
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Background: Inflammatory bowel disease (IBD) is closely associated with spondylarthritis (SpA) and enthesitis, as an important feature of SpA, is a common extraintestinal manifestation of IBD.
Rusmir Husic +6 more
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