Results 141 to 150 of about 317,847 (305)

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

SPONGE-GRAFTING. [PDF]

JAMA: The Journal of the American Medical Association, 1885
openaire   +2 more sources

Development‐based In Vivo Bioreactor Strategy for Challenging Senescent Bone Reconstruction

Advanced Science, EarlyView.
We present a development‐based in vivo bioreactor strategy to generate rejuvenated bone grafts (vBR‐Bone) within aged hosts. By enclosing vBR‐Bone fragments within an asymmetric biomimetic periosteum, segmental femoral defects in aged mice were successfully repaired within 6 weeks. Mechanistically, the multifactors of vBR‐Bone reconstitute a remodeling
Wenchao Zhang, Kai Dai, Tong Shen, Zehua Gao, Fengying Yan, Yuke Feng, Xuanlin Wang, Shaozhen Zhang, Jing Wang, Changsheng Liu   +9 more
wiley   +1 more source

CRISPR/Cas9‐Based Vanadium MXene‐Free Radical Spatiotemporally Controlled Nanoreactor for Photothermal‐Induced Multi‐Effect Synergistic Antitumor Therapy

Advanced Science, EarlyView.
In this study, a MXene‐based V4C3 nanoplatform, VARH, was constructed, which achieved a photothermal conversion efficiency of 44.21% in the NIR‐II window. This platform integrated photothermal therapy, chemodynamic therapy, and thermodynamic therapy with CRISPR/Cas9‐mediated heat shock protein 90 knock‐out technology.
Zi‐Jian Huang, Feng‐Ming Li, Yi‐Fan Tu, Ke‐Ke Feng, Cheng‐Lei Li, Shi‐Cheng Tian, Yong‐Shan Hu, Jing‐Wei Shao, Zhen‐Hua Liu   +8 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Miniaturized 3D Magnetic Force Sensor via Laser‐Assisted Folding and Magnetization for Enhanced Robotic Dexterity

Advanced Science, EarlyView.
To achieve 3D force sensing in confined spaces such as fingertips, we developed a laser‐assisted folding and magnetization method to fabricate miniature films with precise centripetal magnetization. The resulting compact sensor delivers high force resolution, rapid response, and long‐term stability, significantly enhancing the manipulation capabilities
Yujie Huang, Huangzhe Dai, Chengqian Zhang, Daofan Tang, Xinxin Zhang, Haonan Sun, Annan Ding, Xuebin Ni, Yizhi Zhang, Chengfeng Pan, Peng Zhao   +10 more
wiley   +1 more source

MGDP: Mastering a Generalized Depth Perception Model for Quadruped Locomotion

Advanced Science, EarlyView.
ABSTRACT Perception‐based Deep Reinforcement Learning (DRL) controllers demonstrate impressive performance on challenging terrains. However, existing controllers still face core limitations, struggling to achieve both terrain generality and platform transferability, and are constrained by high computational overhead and sensitivity to sensor noise.
Yinzhao Dong, Ji Ma, Yidan Lu, Jiahui Zhang, Wanyue Li, Yeke Chen, Teng Zhang, Xuechao Chen, Zhangguo Yu, Peng Lu   +9 more
wiley   +1 more source

Wearable Tailored Passive Radiative Cooling Textile for Flexible Electronic Integration

Advanced Science, EarlyView.
A scalable, additive‐free wearable tailored passive radiative cooling textile (WRCT) with hierarchically structured fibers delivers exceptional thermal management, combining >95% solar reflectance, 0.96 mid‐infrared emissivity, and ultralow thermal conductivity (0.041 W/m·K).
Lung Chow, Jianpeng Zhang, Zehua Peng, Denglin Ye, Binbin Zhang, Jian Li, Wooyoung Park, Chentao Du, Xingcan Huang, Chun Ki Yiu, Yuze Qiu, Jingkun Zhou, Zhenlin Chen, Yuyu Gao, Weibin Zhu, Pengcheng Wu, Guangyao Zhao, Qiang Zhang, Yuan Guo, Zuowei Sun, Zhan Shen, Shuaiqi Ren, Sang Min Won, Jiyu Li, Xinge Yu   +24 more
wiley   +1 more source

PEMURNIAN DAN KARAKTERISASI INHIBITOR PROTEASE DARI Chromohalobacter sp. 6A3, BAKTERI YANG BERASOSIASI DENGAN SPONS Xetospongia testudinaria [Purification and Characterization of Protease Inhibitor from Chromohalobacter sp. 6A3, Bacteria-associated with Sponge Xetospongia testudinaria]

Jurnal Teknologi dan Industri Pangan, 2010
Various sponges has been reported to produce protease inhibitor which could inhibit protease activity of pathogenic bacteria. The previous research showed that bacteria-associated with sponge could produce bioactive compound similar to their host ...
Tati Nurhayati1)*, Maggy T. Suhartono2), Lilis Nuraida2), Sri Budiarti Poerwanto3)   +3 more
doaj  

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source