Results 191 to 200 of about 359,945 (355)

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

New insights into the microbiome of the deep-sea sponge <i>Inflatella pellicula</i> and the secondary metabolic potential of metagenome-assembled genomes and the wider microbiome. [PDF]

Microb Genom
Jackson SA, Hrab P, Zdouc MM, Clarke DJ, Dobson ADW.   +4 more
europepmc   +1 more source

Alteuthoides affinis, a new peltidiid copepod (harpacticoida) associated with the sponge from Cheju Island, Korea [PDF]

, 1998
Sa Heung Kim, Won Kim
openalex   +1 more source

Characteristics of Carrot Juice Steamed Sponge at Various Doses of Addition of Carrot Juice

, 2023
Muhammad Safari, Rahmah Utami Budiandari
openalex   +1 more source

Cinnamic‐Hydroxamic‐Acid Derivatives Exhibit Antibiotic, Anti‐Biofilm, and Supercoiling Relaxation Properties by Targeting Bacterial Nucleoid‐Associated Protein HU

Advanced Science, EarlyView.
Cinnamic‐hydroxamic‐acid derivatives (CHADs) are identified as novel inhibitors of the bacterial nucleoid‐associated protein HU, exhibiting potent antibacterial, anti‐biofilm (both inhibition and eradication), and DNA relaxation (anti‐supercoiling) activities. Moreover, CHADs demonstrate strong synergistic effects with multiple antibiotics.
Huan Chen, Yingqi Xu, Zhaoping Xiong, Hongliang Wang, Xin Wang, Yue Kang, Zhonglin Wang, Xiaoyan Zeng, Yahui Liu, Yehuan Zheng, Wei Chen, Mengzhe Li, Zhenyue Hu, Chi Xu, Yue Wu, Yawen Wang, Zuyi Yuan, Shuai Yuan, Huadong Liu, Steve Matthews, Nan Qiao, Yan Li, Bing Liu   +22 more
wiley   +1 more source

CircRNA hsa_circ_0070934 functions as a competitive endogenous RNA to regulate HOXB7 expression by sponging miR‑1236‑3p in cutaneous squamous cell carcinoma

, 2020
Dawei Zhang, Haiyan Wu, Chuan‐Rong Zhu, Dongdong Wu   +3 more
openalex   +2 more sources

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

Phased implementation of surgical safety care bundle in a multispecialty, tertiary care teaching hospital: a quality improvement project. [PDF]

BMJ Open Qual
Joselyn AS, Joseph L, Loganathan A, Ebenezer J, Abraham S, Ranjan M.   +5 more
europepmc   +1 more source

Structural stability investigation in bioinspired metamaterials based on glass sponge microstructures

Umberto De Maio, Fabrizio Greco, Francesco Fabbrocino, Raimondo Luciano, Paolo Nevone Blasi, Andrea Pranno   +5 more
openalex   +1 more source

Long noncoding RNA SNHG14 promotes breast cancer cell proliferation and invasion via sponging miR-193a-3p

, 2020
S.-D. Xie, Caipeng Qin, Liping Jin, Qiuju Wang, Jiangnan Shen, Jiali Zhou, Y.-X. Chen, A.-H. Huang, Wanhong Zhao, L.-B. Wang   +9 more
openalex   +1 more source