Results 111 to 120 of about 58,914 (240)

Irradiation Enhances the Biomedical Functional Characteristics of Collagen Sponges: A Potential Strategy for Medical Collagen Sponge Modification. [PDF]

J Funct Biomater
Qin J, Wu H, Lan B, Yao L, Wu Z.
europepmc   +1 more source

Atrophic Skeletal Muscle‐Derived Extracellular Vesicles Transfer miR‐125a‐5p to Inhibit Bone Formation in Osteoporosis during Aging

Advanced Science, EarlyView.
A muscle‐bone endocrine pathway in aging is revealed in which extracellular vesicles released from atrophic skeletal muscle (Aged‐SKM‐EVs) inhibit bone formation. These EVs deliver miR‐125a‐5p to osteoblasts, thereby suppressing the SIRT7‐Sp7 signaling axis and osteogenic differentiation.
Xiaoyan Shao, Pan Zhang, Zhidan Fan, Jiaquan Lin, Xiang Chen, Na Liu, Wang Gong, Yi He, Yining Zhou, Tianshu Shi, Yong Shi, Yuze Ma, Wentian Gao, Haosheng Wang, Depeng Fang, Chengzhi Wang, Wenshu Wu, Wenjin Yan, Jianghui Qin, Dongyang Chen, Haiguo Yu, Qing Jiang, Baosheng Guo   +22 more
wiley   +1 more source

Size‐Modulated Mesoderm‐Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids

Advanced Science, EarlyView.
Micropatterned cardioids, CRISPR‐engineered reporter hiPSCs, deep‐tissue imaging, and single‐cell RNA sequencing are integrated to model mesoderm‐endoderm co‐development. Heart‐foregut crosstalk promotes single large cavitation inside cardioids, resembling early heart chamber formation. ABSTRACT The human heart, originating from the splanchnic mesoderm,
Plansky Hoang, David W. McKellar, Andrew Kowalczewski, Nhu Y. Mai, Meng Chai, Xiaojun L. Lian, Yi Zheng, Jeffrey Amack, Nathan Tucker, Iwijn De Vlaminck, Huaxiao Yang, Benjamin D. Cosgrove, Zhen Ma   +12 more
wiley   +1 more source

Molecular and spatial integration of algal endosymbionts of the freshwater sponge, Ephydatia muelleri, throughout development in light and dark conditions. [PDF]

BMC Genomics
Horton AL, Neighmond H, Neighmond A, Anderson R, Lessard M, Price V, Leys SP, Riesgo A.   +7 more
europepmc   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source

Unveiling in situ oxygen, carbon and nutrient cycling of a sponge-driven biological hotspot in the arctic. [PDF]

Sci Rep
Hanz U, Mueller B, Bart MC, Busch K, Reichart GJ, Rapp HT, de Goeij JM, Mienis F.   +7 more
europepmc   +1 more source

Cohort‐Scale Spatial Autocorrelation for Tumor Prediction in Mid‐Infrared Pathology and Spatial Biomarker Discovery Using MALDI Imaging Lipidomics

Advanced Science, EarlyView.
Computational annotation of various tissue types in heterogeneous samples such as colorectal cancer liver metastasis (CRLM) using spatial autocorrelation analysis on non‐destructive mid‐infrared (MIR) imaging data enabled correlative multimodal mass spectrometry imaging (MSI) for spatial investigation of lipid tumor marker candidates. The method can be
Miriam F. Rittel, Nikolas Ebert, Denis Abu Sammour, Sebastian Graf, Björn C. Fröhlich, Emrullah Birgin, Shad A. Mohammed, Nuh N. Rahbari, Axel Wellmann, Oliver Wasenmüller, Cleo‐Aron Weis, Stefan Schmidt, Carsten Hopf   +12 more
wiley   +1 more source

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Nanoarchitectonics of Porous Carbons Templated by Inorganic Metal Oxides and Alkali Metal Salts for Energy and Environmental Applications

Advanced Science, EarlyView.
This review explores inorganic metal oxides and metal salt nanoparticles templated porous carbons, highlighting their synthesis, structural features, and performance in energy and environmental applications. It critically compares template types, porosity control, and functional outcomes across recent literature.
Gurwinder Singh, Jibi Kunjumon, Harleen Kaur, Narinder Singh, Gregory Franklin, Arpita Pandey Tiwari, Lukas Van Zweiten, John Kennedy, Ajayan Vinu   +8 more
wiley   +1 more source

Bioinspired Microreactor for Iodide Adsorption and Photooxidation Recovery

Advanced Science, EarlyView.
A bioinspired micro‐ionic‐reactor based on porous organic polymer (MIR‐POP) integrates rapid iodide capture with in situ photooxidative conversion, achieving record uptake capacity and high uptake efficiencies in simulated mining wastewater and natural brine. This bioinspired microreactor strategy offers a new avenue for sustainable iodine recovery and
Xuewen Cao, Xuefeng Tian, Jun Zhang, Jinjiao Pan, Rui Huang, Xinfeng Du, Yihui Yuan, Ning Wang, Hui Wang   +8 more
wiley   +1 more source