Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley +11 more
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The emerging role of circular RNAs in neurodegenerative diseases and viral infections. [PDF]
Medina F, Bellizzi A.
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Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab +8 more
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Hydrophobic modification of a polyurethane sponge <i>via</i> emulsion polymerization for selective oil-water separation. [PDF]
Islam Setu MA +5 more
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Ammonia oxidation and recalcitrant carbon degradation fuel mixotrophic growth in the symbiont community of a deep-sea sponge. [PDF]
Garritano AN +11 more
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Tracking pathogen-related markers with eDNA in natural areas: how environmental factors shape surveillance strategies. [PDF]
Perelló A +13 more
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Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui +9 more
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Health Risks of Organophosphate Flame Retardants (OPFRs) in Facial Cosmetic Sponges via Dermal Exposure. [PDF]
Yang Y +9 more
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Substrate‐Dependent Crosslinking by the Cytochrome P450 From Aminopyruvatide Biosynthesis
Substitutions in the aminopyruvatide precursor peptide altered the C─C linkage formed from a YLY motif by the P450 ApyO to a N─C linkage in a WLY motif. Moreover, constitutional isomers crosslinked by C─C and C─O linkages were formed from YYY or YWY motifs. ABSTRACT Cytochrome P450s catalyze an array of reactions including crosslinking of aromatic side
Chandrashekhar Padhi +6 more
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An expert-curated dataset of glass sponges (Porifera, Hexactinellida) distribution across the Atlantic and Arctic Oceans. [PDF]
Domingos C +3 more
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