Results 241 to 250 of about 82,505 (312)

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Fragment-Based Online OzESI-MS, NMR, and Computational DP4+/DFT Approaches to the Characterization of the Putative Biosynthetic Lipid Precursor of Atkamine from Alaskan <i>Latrunculia</i> Sponges. [PDF]

ACS Omega
Benjamin MM, Dickinson CF, Wood JS, Williamson RT, Hanna GS, Alford AS, Stone RP, Hoff GR, Samala AR, Mulani FA, Zhang Q, Hamann MT.   +11 more
europepmc   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

BMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing, Yuhui Yang, Ziyi Zhao, Kai Lv, Yiran Shao, Zhi Zhang, Dong Ma   +6 more
wiley   +1 more source

Innovations in Silicon Transport Shaped the Rise of Biosilicification and Skeletal Evolution in Sponges. [PDF]

Mol Biol Evol
Leria L, Maldonado M.
europepmc   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Independent origins of spicules reconcile paleontological and molecular evidence of sponge evolutionary history. [PDF]

Sci Adv
Rossi ME, Keating JN, Kenny NJ, Giacomelli M, Álvarez-Carretero S, Schuster A, Cárdenas P, Taboada S, Koutsouveli V, Donoghue PCJ, Riesgo A, Pisani D.   +11 more
europepmc   +1 more source

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial–mesenchymal transition and pulmonary niche formation of breast cancer

Biological Reviews, EarlyView.
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu, Reza Shirazi Nia, Junjie Sun, Chrysa Filippopoulou, Daniel De Vega, Pengtao Hu, Heng Liang, Hang Yao, Chaoyue Pan, Xiaoyan Wu, Xidong Gu, Xiaohong Xie, Georgios Giamas   +12 more
wiley   +1 more source

Isolation, Characterization and Biological Evaluation of Collagen from <i>Rhizostoma pulmo</i> Jellyfish from the Sea of Azov for Biomedical Applications. [PDF]

Mar Drugs
Kit O, Golovin S, Kirichenko E, Sereda A, Gordeeva Y, Sadyrin E, Nikolaev A, Antipov P, Logvinov A, Kaplya M, Abdulkadyrov M, Rodkin S.   +11 more
europepmc   +1 more source

Utterance evolution: the road to generative, combinatorial communicators

Biological Reviews, EarlyView.
ABSTRACT Language has long been considered uniquely complex in the animal kingdom; however, animal research over the last decade has begun to challenge some long‐standing premises about exactly which language capacities are uniquely human. The task of resolving why and how complex communication systems evolve, particularly human language, has ...
Catherine Crockford, Roman Martin Wittig, Cedric Girard‐Buttoz   +2 more
wiley   +1 more source

Statistical invisibility and surgical harm: gossypiboma and the hidden safety crisis for women in Pakistan. [PDF]

Ann Med Surg (Lond)
Adnan Z, Kashif A, Raza AA, Samadi A.
europepmc   +1 more source