Results 41 to 50 of about 124,079 (304)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Therapeutic theatre and spontaneity: Goethe and Moreno [PDF]

open access: yes, 2006
Moreno noted a similarity between a late 18th Century play by the great German scholar and artist, Goethe, and some elements of psychodrama, which can be substantiated; however, Goethe was not, as Moreno suggested, an early promoter of spontaneity.
Scheiffele, Eberhard
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Science under caesar-politarch's patronage

open access: yesАнтиномии, 2020
The subject of this article is the specificity of socio-cultural situation in which the individual professionally engaging in natural sciences and mathematics does act in politary society (ancient Egypt, ancient India and China, medieval Arab-Muslim ...
Vyacheslav Y. Vasechko
doaj   +1 more source

Spiritual Well-Being, Self-Esteem and Intimacy Among Couples Using Natural Family Planning [PDF]

open access: yes, 1994
Making decisions about achieving and avoiding pregnancy and the methods used to attain those ends are some of the most central decisions during a couple\u27s reproductive life.
Fehring, Richard J., Lawrence, Donna M.
core   +2 more sources

gruntCount (bass clarinet Edition): blurring the piece, system, instrument distinction [PDF]

open access: yes, 2014
Martin Parker’s gruntCount is a multi-version, configurable composition for improvising musician (or musicians) and computer. Performers embark on a journey through sound processing modules that are specifically customised to individual playing styles ...
Parker, Martin, Peter, Furniss,
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The role of order and disorder in thermal and material sciences part 1: Heat and society [PDF]

open access: yesJournal of Mining and Metallurgy. Section B: Metallurgy, 2002
The notion of heat is thoroughly analyzed and its historical links are searched particularly with relation to both the Greek philosophy (Milesians, Pythagoreans, atomists, etc.) and in the present day thermal physics.
Šesták J.
doaj   +1 more source

Spontaneous pneumothorax [PDF]

open access: yesMultidisciplinary Respiratory Medicine, 2011
Pneumothorax is defined as the presence of air in the pleural space due to: a) communication be- tween alveolar spaces and pleura; b) direct or indi- rect exchange of air between the atmosphere and the pleural space; or c) the presence of gas produc- ing organisms in the pleural space.
openaire   +4 more sources

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