Results 31 to 40 of about 1,181,988 (318)

Spontaneous mid‐trimester uterine rupture associated with fetal death in a young patient during COVID‐19 pandemic: A case report

open access: yesClinical Case Reports, 2022
Uterine rupture mostly occurs in the third trimester. However, it may occur at an earlier time with the same catastrophic consequences. The authors present a case report of uterine rupture occurring in the second trimester at 18 weeks gestation.
Ahmed Dheyaa Al‐Obaidi   +3 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Tunisian Silybum Species: Important Sources of Polyphenols, Organic Acids, Minerals, and Proteins across Various Plant Organs

open access: yesPlants
Silybum marianum and Silybum eburneum are wild edible Mediterranean plants used in the human diet. This study presents the initial findings on the phytochemical characterization of Tunisian S. marianum and S. eburneum organs.
Samah Maaloul   +9 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Organ-dependent variability in mineral composition, phytochemicals and antioxidant potentials in Polygonum equisetiforme parts

open access: yesInternational Journal of Plant Based Pharmaceuticals
Polygonum equisetiforme is a perennial herbaceous plant thriving in the arid regions of Tunisia and widely used in health care and self-medication. The objective of the current study was to investigate the distribution of minerals, phenolic compounds ...
Maher Mahmoudi   +5 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Case of benralizumab‐induced exacerbations of chronic spontaneous urticaria

open access: yesClinical Case Reports, 2022
The role of IL‐5 in chronic spontaneous urticarial (CSU) is unclear. It may be that benralizumab is an important bidirectional modifier of CSU; that is, blocking IL‐5 may improve CSU in some patients, but it is possible that it may worsen CSU in others.
Eli Magen   +3 more
doaj   +1 more source

Spontaneous pneumothorax [PDF]

open access: yesMultidisciplinary Respiratory Medicine, 2011
Pneumothorax is defined as the presence of air in the pleural space due to: a) communication be- tween alveolar spaces and pleura; b) direct or indi- rect exchange of air between the atmosphere and the pleural space; or c) the presence of gas produc- ing organisms in the pleural space.
openaire   +4 more sources

The influence of spontaneous and visual activity on the development of direction selectivity maps in mouse retina [PDF]

open access: gold, 2022
Alexandre Tiriac   +4 more
openalex   +1 more source

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