Results 61 to 70 of about 2,521,623 (328)
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Sensory memory for odors is encoded in spontaneous correlated activity between olfactory glomeruli [PDF]
, 2006 Sensory memory is a short-lived persistence of a sensory stimulus in the nervous system, such as iconic memory in the visual system. However, little is known about the mechanisms underlying olfactory sensory memory.
Galizia, C. Giovanni +4 more
core +1 more source
Experimental autoimmune uveitis and other animal models of uveitis: An update
Indian Journal of Ophthalmology, 2015 Over the past several decades, animal models of autoimmune uveitis directed at eye-specific antigens (Ags) have been developed. These have allowed researchers to understand the basic mechanisms that lead to these diseases and also recently helped the ...
Svati Bansal +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Mechanical shock during egg de-adhesion and post-ovulatory ageing contribute to spontaneous autopolyploidy in white sturgeon culture (Acipenser transmontanus) [PDF]
, 2020 Spontaneous autopolyploidy, a 1.5x increase in genome size resulting from second polar body retention after fertilization, has been documented in cultured sturgeons, with the proportion of spontaneous autopolyploid progeny ranging widely among maternal ...
Conte, FS +6 more
core
Lung India, 2016 Rupture of pyriform sinus due to forced effort with closed glottis has been reported but is extremely rare. We report a case of rupture of pyriform sinus following multiple episodes of vomiting with subsequent development of pyopneumothorax.
Rahul Tyagi +3 more
doaj +1 more source
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Spontaneous Resolution of Massive Spontaneous Tubercular Pneumothorax [PDF]
Case Reports in Pulmonology, 2011 A 29-year-old female presented with complaints of fever and productive cough of three weeks duration. Pulmonary tuberculosis was diagnosed bacteriologically and she was prescribed antituberculosis drugs. During follow-up she developed massive pneumothorax, for which patient refused surgical management and was managed conservatively.
Surya Kant +3 more
openaire +3 more sources
Noise enhanced spontaneous chaos in semiconductor superlattices at room temperature
, 2014 Physical systems exhibiting fast spontaneous chaotic oscillations are used to generate high-quality true random sequences in random number generators. The concept of using fast practical entropy sources to produce true random sequences is crucial to make
Alvaro, M. +2 more
core +1 more source
Quasiclassical Theory of Spontaneous Currents at Surfaces and Interfaces of d-Wave Superconductors [PDF]
, 2002 We investigate the properties of spontaneous currents generated at surfaces and interfaces of d-wave superconductors using the self-consistent quasiclassical Eilenberger equations.
A.M. Zagoskin +53 more
core +1 more source