Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging
Fatty acid β‐oxidation was elevated in cumulus cells from older mice. Tryptophan metabolism in aged cumulus cells was active. Supplementing with 5‐HT could mitigate aging damage in oocytes. ABSTRACT Maternal age has been reported to impair oocyte quality.
Liangyue Shi+6 more
wiley +1 more source
Increased Trophoblast Cell Ferroptosis via HMGB1/ACSL4 Pathway Is Associated with Spontaneous Abortion. [PDF]
Dong Y, Li Y, Tang W, Chen Q, Kong C.
europepmc +1 more source
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan+5 more
wiley +1 more source
Alarmins and their pivotal role in the pathogenesis of spontaneous abortion: insights for therapeutic intervention. [PDF]
Zhang Q+12 more
europepmc +1 more source
Management of reccurent spontaneous abortion. The efficacy and the problem of immunotherapy.
Toshiyuki Takeshita+2 more
openalex +2 more sources
Causal Effects of Inflammatory Cytokines and Immune Cell Phenotypes on Spontaneous Abortion: Evidence From Mendelian Randomization. [PDF]
Lin S+9 more
europepmc +1 more source
Autonomic biosignals, seizure detection, and forecasting
Abstract Wearable devices have attracted significant attention in epilepsy research in recent years for their potential to enhance patient care through improved seizure monitoring and forecasting. This narrative review presents a detailed overview of the current clinical state of the art while addressing how devices that assess autonomic nervous system
Gadi Miron+4 more
wiley +1 more source
circFTO binding with IGF2BP2 regulates trophoblast cells proliferation, migration, and invasion while mediating m6A modification of CCAR1 mRNA in spontaneous abortion. [PDF]
Zhang Y+9 more
europepmc +1 more source