Results 271 to 280 of about 1,078,782 (407)

Biallelic COL4A2 Variants Associated With Brain Small Vessel Disease and Brain Malformations

open access: yesClinical Genetics, EarlyView.
Biallelic COL4A2 variants cause a spectrum of brain abnormalities such as brain small vessel disease (BSVD). We describe two cases—one with cerebrovascular disruption and one with cortical malformations—expanding the recessive phenotype. Protein modeling reveals destabilization by p.(Arg179Cys), reinforcing its pathogenic role and highlighting collagen
Anees Muhammad   +11 more
wiley   +1 more source

Attune, animate and amplify: Creating youth voice assemblages in pARTicipatory sexuality education research

open access: yesChildren &Society, EarlyView.
Abstract This paper explores the politics and praxis of ‘youth voice assemblages’ in an exploratory and pARTicipatory research project where 125 young people (aged 11–18) from England, Scotland and Wales shared what and how they are learning about relationships, sex and sexuality.
EJ Renold   +5 more
wiley   +1 more source

The frequency of acute atherosis in normal pregnancy and preterm labor, preeclampsia, small-for-gestational age, fetal death and midtrimester spontaneous abortion*

open access: yesJournal of Maternal-Fetal & Neonatal Medicine, 2015
Y. M. Kim   +12 more
semanticscholar   +1 more source

Autophagy in PE: Dispute, Role and Potential Target

open access: yesCell Proliferation, EarlyView.
Autophagy homeostasis serves as a central hub regulating vascular remodelling during pregnancy. It integrates maternal, genetic, and fetal factors; shapes the functions of immune cells (NK cells, macrophages, and T cells); restrains endothelial inflammatory responses (cytokines, endothelial cell, oxidative/ER stress, and protein aggregation); and ...
Miao Xu   +12 more
wiley   +1 more source

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