Results 51 to 60 of about 694,029 (300)

DDN gene downregulation in endometrium: a potential immune-mediated link between bipolar disorder and spontaneous abortion revealed by Mendelian randomization and bioinformatics

Beni-Suef University Journal of Basic and Applied Sciences
Background Spontaneous abortion, affecting over 20% of pregnancies, presents significant physical and psychological burdens. While chromosomal aneuploidy and environmental factors contribute to its etiology, the role of maternal genetic and psychiatric ...
Jian Tang, Zhixin Xu, Lingling Yang, Qiong Zou   +3 more
doaj   +1 more source

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit, Daphna Idan, Ariel Avraham Hasidim, Tal Michael, Amalia Levy, Gali Pariente, Eitan Lunenfeld, Sharon Daniel   +7 more
wiley   +1 more source

Differences In Serum IL-6 Levels Between First-Trimester Normal Pregnancy and Spontaneous Abortion

Andalas Obstetrics and Gynecology Journal
Objectives: In spontaneous abortion cases without previously known predisposing factors, an increase proinflammatory cytokines, especially interleukin 6 (IL-6), found in local and systemic specimens compared to normal 1st -trimester pregnancies ...
Vella Amalia, Bobby Indra Utama, Dessy Arisanty, Nelmi Silvia   +3 more
doaj   +1 more source

Unintended Pregnancies and Breastfeeding Studies during Central Nervous System Drug Development: How Are they Handled, Is There Room for Improvement?

Clinical Pharmacology &Therapeutics, EarlyView.
Pregnant and breastfeeding individuals are routinely excluded from clinical drug development, creating persistent evidence gaps in pharmacology, safety, and dosing. Despite mandatory contraception and pregnancy testing, unintended pregnancies occur, particularly during the development of central nervous system (CNS) medicines used by women of ...
Sam Schoenmakers, Charlotte Bakker, Alexandra Ganev, Florence Butlen‐Ducuing, Corinne S. de Vries   +4 more
wiley   +1 more source

Association between Abortion and All-Cause and Cause-Specific Premature Mortality: A Prospective Cohort Study from the UK Biobank

Health Data Science
Background: Concerns have been raised about the increasing prevalence of both spontaneous and induced abortions worldwide, yet their effect on premature mortality remains poorly understood.
Shaohua Yin, Yingying Yang, Qin Wang, Wei Guo, Qian He, Lei Yuan, Keyi Si   +6 more
doaj   +1 more source

Exploring Cultural and Individual Differences in the Hierarchy of Moral Concern: Evidence From Student Samples Across 41 Cultural Groups

European Journal of Social Psychology, EarlyView.
ABSTRACT Many important historical and contemporary ethical debates (e.g., on slavery, abortion and environmental protection) reflect disagreements about what we owe to different groups of individuals. Recent work in moral psychology has uncovered a seemingly replicable hierarchy of moral concern, but these studies were conducted in a few countries ...
Işıl Ayça Akkuş, Charlie R. Crimston, Kelly Kirkland, Brock Bastian, Bastian Jaeger   +4 more
wiley   +1 more source

Abortion services in South Africa : challenges and barriers to safe abortion care : health care providers' perspectives [PDF]

, 2010
Includes bibliographical references (leaves 199-213).Unsafe abortion is a preventable phenomenon and continues to be a major public health problem in many countries especially in the developing world.
Harries, Jane
core   +1 more source

Association between early spontaneous abortion and homocysteine metabolism

Frontiers in Medicine
ObjectiveThe purpose of this study is to explore the effects of homocysteine (HCY) metabolism and related factors on early spontaneous abortion.MethodsWe conducted a hospital-based case–control study and included a total of 500 cases and 1,000 controls ...
Fangliang Lei, Fangliang Lei, Lili Zhang, Li Wang, Wentao Wu, Fei Wang, Fei Wang   +6 more
doaj   +1 more source

Increased Circulating Levels of Tissue-Type Plasminogen Activator Are Associated with the Risk of Spontaneous Abortion During the First Trimester of Pregnancy

Diagnostics, 2020
Spontaneous abortion is a common complication in early pregnancy, with an incidence of around 20%. Ultrasound scan and measurement of human chorionic gonadotropin are used to identify patients at risk of spontaneous abortion; however, there is a clinical
Lara J. Monteiro, Manuel Varas-Godoy, Stephanie Acuña-Gallardo, Paula Correa, Gianluca Passalacqua, Max Monckeberg, Gregory E. Rice, Sebastián E. Illanes   +7 more
doaj   +1 more source

Spontaneous Abortion Cases with Fetal Chromosomal Aneuploidy.

, 2013
Spontaneous Abortion Cases with Fetal Chromosomal Aneuploidy.
You Jung Han (195038), Min Hyoung Kim (283284), Hyun Mee Ryu (195047), So Yeon Park (195028), Moon Young Kim (195043), Ji Hyae Lim (195020), Da Eun Lee (283285), Jung Yeol Han (283286)   +7 more
core   +1 more source