Results 81 to 90 of about 1,697,405 (342)

Iron homeostasis in pregnancy and spontaneous abortion

American journal of hematology/oncology, 2018
During pregnancy, iron requirements are increased to support maternal erythropoietic expansion and fetal growth and development. To meet these requirements, dietary iron absorption increases, and available iron stores are mobilized. These adjustments are
Yi-Fan Guo, Na Zhang, Daoqiang Zhang, Quanzhong Ren, T. Ganz, Sijin Liu, E. Nemeth   +6 more
semanticscholar   +1 more source

The Role of IgM Anti‐acetylated Protein Antibodies and B Cells in the Origin of Antimodified Protein Autoimmunity in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid arthritis (RA) is characterized by anti‐modified protein antibodies (AMPAs), including anti‐citrullinated protein antibodies (ACPA), anti‐carbamylated protein antibodies (anti‐CarP), and anti‐acetylated protein antibodies (AAPA). In contrast to other AMPAs, AAPA IgM is found in healthy individuals, raising questions about its role ...
Aegli Athanasiadou, Sanne Kroos, Renee van de Wetering, Rian Schopmeijer, Carin van der Keur, Michael Eikmans, Caroline Meijer, Solbritt Rantapää‐Dahlqvist, René E. M. Toes, Linda M. Slot, Diane van der Woude   +10 more
wiley   +1 more source

Risk of Spontaneous Abortion After Inadvertent Human Papillomavirus Vaccination in Pregnancy

Obstetrics and Gynecology, 2018
Objective To evaluate the risk of spontaneous abortion after quadrivalent human papillomavirus (4vHPV) vaccination before and during pregnancy across seven integrated health systems within the Vaccine Safety Datalink.
Elyse O. Kharbanda, G. Vazquez-Benitez, H. Lipkind, Sangini S. Sheth, Jing-Yi Zhu, A. Naleway, N. Klein, R. Hechter, Matthew F. Daley, J. Donahue, M. Jackson, A. Kawai, Lakshmi Sukumaran, J. Nordin   +13 more
semanticscholar   +1 more source

Characteristics and temporal trends of EU teratological safety signals and information dissemination to healthcare professionals in the Netherlands—A contribution of the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Although regulatory responses to safety signals have been studied, pregnancy‐specific data and their dissemination to medical professionals remain unclear. This study examined the characteristics and temporal trends of teratological safety signals prompting the European Medicines Agency to implement risk minimization measures.
Yrea R. J. van Rijt‐Weetink, Rosanne E. Huisman, Jan‐Peter van Wieringen, H. J. M. J. (Ineke) Crijns, Florence P. A. M. van Hunsel, Anneke L. M. Passier, Sander Borgsteede, A. C. G. (Toine) Egberts, Laura M. Yates, Eugène P. van Puijenbroek   +9 more
wiley   +1 more source

Maternal Dipyrone Exposure and Risk of Major Congenital Malformations, Adverse Perinatal and Postnatal Outcomes: A Population‐Based Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Pain and fever are common in pregnancy. Dipyrone is widely used in Europe, Latin America, and parts of Asia, but is banned in other countries due to concerns about agranulocytosis. Evidence on its safety in pregnancy remains limited and inconsistent. This study aimed to evaluate whether maternal dipyrone use during the first‐ and third‐trimesters is ...
Itamar Ben Shitrit, Daphna Idan, Ariel Avraham Hasidim, Tal Michael, Amalia Levy, Gali Pariente, Eitan Lunenfeld, Sharon Daniel   +7 more
wiley   +1 more source

Differences In Serum IL-6 Levels Between First-Trimester Normal Pregnancy and Spontaneous Abortion

Andalas Obstetrics and Gynecology Journal
Objectives: In spontaneous abortion cases without previously known predisposing factors, an increase proinflammatory cytokines, especially interleukin 6 (IL-6), found in local and systemic specimens compared to normal 1st -trimester pregnancies ...
Vella Amalia, Bobby Indra Utama, Dessy Arisanty, Nelmi Silvia   +3 more
doaj   +1 more source

Comparison of food intake and body mass index before pregnancy between women with spontaneous abortion and women with successful pregnancy [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2017
Introduction:Spontaneous abortion or pregnancy loss is defined as the natural death of fetus before 20th weeks of pregnancy. There is a possibility that food intake is related to spontaneous abortion.
Shirin Amini, Sima Jafarirad, Houra Mohseni, Hajar Ehsani, Ladan Hejazi, Nahid Feghhi   +5 more
doaj   +1 more source

Reproductive Factors and Risk of Spontaneous Abortion in the Jinchang Cohort

International Journal of Environmental Research and Public Health, 2018
The aim of this study was to investigate the association between female reproductive status and risk of spontaneous abortion among female workers in the Jinchang Cohort. This study used data obtained from a baseline survey of the Jinchang Cohort Study of
Xiao-Bin Hu, M. Miao, Ya-Na Bai, N. Cheng, Xiaowei Ren   +4 more
semanticscholar   +1 more source

An algorithm for seizure detection in rodents

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky, Gerben van Hameren, Itai Weissberg, Pooyan Moradi, Ofer Prager, Alaa Abu Ahmad, Lior Schori, Albert Becker, Yaniv Zigel, Alon Friedman   +9 more
wiley   +1 more source

Antioxidant Defenses, Oxidative Stress Responses, and Apoptosis Modulation in Spontaneous Abortion: An Immunohistochemistry Analysis of First-Trimester Chorionic Villi

Life
Oxidative stress (OS) and apoptosis are critical factors in placental development and function. Their interplay influences trophoblast proliferation, differentiation, and invasion, as well as vascular development. An imbalance between these processes can
Ioana Vornic, Alexandru Nesiu, Ana Maria Ardelean, Oana Cristina Todut, Victoria Cristina Pasare, Cristina Onel, Ionuț Daniel Raducan, Cristian George Furau   +7 more
doaj   +1 more source