Results 51 to 60 of about 56,202 (277)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Spontaneously Opening and Closing Macular Holes with Lamellar Hole Epiretinal Proliferation: A Longitudinal Optical Coherence Tomography Analysis

Diagnostics
Background/Objectives: Spontaneous macular hole closure is a rare phenomenon, with lamellar hole epiretinal proliferation (LHEP) frequently implicated as a potential mechanism.
Omar Moussa, Jedrzej Golebka, Gabriel Gomide, Dvir Koenigstein, Hueyjong Shih, Royce W. S. Chen   +5 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Delayed Amplatzer device closure of atrial septal defect for persistent cyanosis after surgical correction of severe pulmonary stenosis in early infancy [PDF]

, 2004
This article presents two patients who had delayed transcatheter closure of secundum atrial septal defects for persistent cyanosis after surgical repair of severe pulmonary stenosis.
DeGiovanni, Joseph V., Grech, Victor E., Falzon, A.   +2 more
core  

Spontaneous closure of the hymen during term pregnancy

, 2017
The hymen is a thin fold of mucous membrane; partially closing the external vaginal opening.1It is composed mainly of elastic, collagenous connective tissue and covered on its both surfaces by stratified squamous epithelium.
Shilpa G., G., Shilpa, Gomathy E., Liston, Poonguzhali, E., Gomathy, Poonguzhali Liston   +5 more
core   +1 more source

Brain Spontaneous Intracranial Hypotension Score for Treatment Monitoring After Surgical Closure of the Underlying Spinal Dural Leak. [PDF]

, 2022
BACKGROUND Spontaneous intracranial hypotension (SIH) is a debilitating condition requiring effective treatment; however, objective data on treatment response are scarce.
Ulrich, Christian, Dobrocky, Tomas, Branca, Mattia, Gralla, Jan, Beck, Jürgen, Pilgram-Pastor, Sara, Kaesmacher, Johannes, Rohner, Roman, Piechowiak, Eike I., Raabe, Andreas, Häni, Levin, Mordasini, Pasquale, Cianfoni, Alessandro, Schär, Ralph T.   +13 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

SD-OCT imaging of idiopathic macular holes with spontaneous closure.

, 2012
Spectral-domain optical coherence tomography serial changes in three cases of spontaneous closure of idiopathic macular hole at stages II, III, and IV are described.
Scupola A, Balestrazzi E., Da Dalt S, Sasso P, BOZZONI PANTALEONI, Francesco, Mastrocola A, Tiberti AC, Berarducci A   +7 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The role of vitreous cortex remnants in secondary macular hole formation and spontaneous closure following vitrectomy for rhegmatogenous retinal detachment

Photodiagnosis and Photodynamic Therapy
Background: Macular hole (MH) formation after rhegmatogenous retinal detachment (RRD) surgery is rare, and in most cases, additional surgical procedures are required to repair MH. Spontaneous closure of the MH is even rarer.
Bing Xu, Yiyan Wang, Yang Cheng, Qiong Huang   +3 more
doaj   +1 more source