Results 161 to 170 of about 1,402 (263)

Bound by blood and bloodshed: Sibling ties and participation in genocidal violence

Criminology, EarlyView.
Abstract Focusing on the 1994 genocide in Rwanda, we examine how sibling relationships—one of the most salient familial bonds—influence individual engagement in violence during mass atrocity. Drawing on an adaptation of differential association and social learning theories for contexts of mass atrocity, we analyze a novel dataset linking over 300,000 ...
Jack G. R. Wippell, Hollie Nyseth Nzitatira, Jared F. Edgerton, Evelyn Gertz   +3 more
wiley   +1 more source

Kaempferol Protects Intestinal Health in Chinese Forest Musk Deer Possibly by Regulating Intestinal Microbiota and Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Integrative Zoology, EarlyView.
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu, Zhanjun Ren, Xiuzhu Sun, Shuhui Wang   +3 more
wiley   +1 more source

Changing public perceptions of alcohol, alcohol harms and alcohol policies: A multi‐methods study to develop novel framing approaches

Addiction, Volume 120, Issue 4, Page 655-668, April 2025.
Abstract Background and aims Public perceptions of alcohol and its related harms and policies are shaped by multiple discourses and can influence behaviour and policy support. As part of a FrameWorks‐informed project to test framing approaches to improve public understanding and support for evidence‐based alcohol policies in the UK, this research aimed
Niamh Fitzgerald, Kathryn Angus, Rebecca Howell, Heather Labhart, James Morris, Laura Fenton, Nicholas Woodrow, Maria Castellina, Melissa Oldham, Claire Garnett, John Holmes, Jamie Brown, Rachel O'Donnell   +12 more
wiley   +1 more source

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens, Dahbia Belahda, Carine Graux, Noe Igounenc, Chris Serrand, Paul Rochefort, Thibault Mura, Felix Sergent   +7 more
wiley   +1 more source

Low and no alcohol availability and sales in small retailers in Great Britain: A geographic longitudinal analysis from 2018 to 2022

Addiction, EarlyView.
Abstract Background and aims The United Kingdom Government is committed to reducing alcohol consumption through increasing the availability of alcohol‐free and low‐alcohol (No/Lo) drinks; however, little is known about whether these products are equally available across different types of neighbourhoods, which may have implications for inequalities in ...
Roberto Valiente, Helena Tunstall, Luke B. Wilson, Duncan Gillespie, Jamie Pearce, Niamh K. Shortt   +5 more
wiley   +1 more source

Assessing Major Adverse Liver Outcomes With Baclofen Compared to Acamprosate in Compensated Alcohol‐Associated Cirrhosis

Alimentary Pharmacology &Therapeutics, EarlyView.
We conducted a nationwide, multicenter cohort study using a target trial emulation framework to compare baclofen and acamprosate in patients with compensated alcohol‐associated cirrhosis. After matching, baclofen initiation was associated with a higher 1‐year risk of major adverse liver outcomes, driven primarily by hepatic encephalopathy, particularly
Yee Hui Yeo, Sepideh Mehravar, Ellen Choi, Ju Dong Yang, Hyun‐Seok Kim, Yun Wang, Aarshi Vipani, Hirsh D. Trivedi, Walid Ayoub, Parnian Naji, Alexander Kuo, Chun‐Ying Wu, Lorenzo Leggio, Juan Pablo Arab   +13 more
wiley   +1 more source

Spontaneous imbibition in fractal tortuous micro-nano pores considering dynamic contact angle and slip effect: phase portrait analysis and analytical solutions. [PDF]

Sci Rep, 2018
Li C, Shen Y, Ge H, Zhang Y, Liu T.
europepmc   +1 more source

Digital Doppelgängers, Human Relationships, and Practical Identity

Bioethics, EarlyView.
ABSTRACT In this paper, we examine the potential effects of relationships with Large Language Model (LLM)‐based digital doppelgängers (DDs) on users' values, concerns, and interests, that is, on their practical identity. DDs are artificially intelligent conversational agents trained on individuals' data to replicate their speech patterns, mannerisms ...
Cristina Voinea, Sebastian Porsdam Mann, Julian Savulescu, Brian D. Earp   +3 more
wiley   +1 more source

Out There No One Has a Right to Die

Bioethics, EarlyView.
ABSTRACT The eventual goal of space exploration is to colonize exoplanets and their moons outside our solar system. This is a dangerous and immoral endeavour. The extraterrestrial life forms encountered would be hostile, vulnerable or both, and the descendants of the original pioneers would be involuntarily exposed to hazardous conditions and ...
Matti Häyry
wiley   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source