Results 171 to 180 of about 1,402 (263)

Targeting the noradrenergic‐metabolic axis: A new strategy for sugar‐induced depression subtypes

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Lifestyle is closely related to major depressive disorder (MDD). Given the growing focus on the impact of diet on mental health, this study examined how dietary habits affect the pathophysiology of MDD. Experimental Approach Health check‐up data were analysed. Mice received sucrose under chronic unpredictable mild stress
Takatoshi Sakata   +13 more
wiley   +1 more source

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

open access: yesBritish Journal of Pharmacology, EarlyView.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva   +10 more
wiley   +1 more source

Entrepreneurial State as a Creative Destroyer: Comparison of Hong Kong and Singapore's Creative Industries

open access: yesCreativity and Innovation Management, EarlyView.
ABSTRACT This paper explores the limits of mission‐directed entrepreneurial states by drawing on the theory of recombinant innovation and F.A. Hayek's insights on the spontaneous growth of knowledge in society. First, the use of discretionary policymaking curtails the range of knowledge generated in the process of social interaction, limiting the scope
Bryan Cheang, Praharsh Mehrotra
wiley   +1 more source

Disentangling the Relationship Between Mindfulness and Creativity: The Role of Conceptual and Experimental Creative Methods

open access: yesCreativity and Innovation Management, EarlyView.
ABSTRACT Prior research has indicated that mindfulness has the potential to enhance individuals' functioning in many ways. However, explorations of its relationship with creativity have elicited contrasting results that remain unresolved, and the underlying processes of this relationship remain unclear.
Aldijana Bunjak   +3 more
wiley   +1 more source

How do Artificial Intelligence chatbots respond to questions from adolescent personas about their eating, body weight or appearance?

open access: yesChild and Adolescent Mental Health, EarlyView.
Background Body image and eating behaviours are common areas of concern for early adolescents. Artificial Intelligence (AI) interactions are becoming commonplace, including with chatbots that provide human‐like communication. Adolescents may prefer using chatbots to anonymously ask sensitive questions, rather than approaching trusted adults or peers ...
Florence Sheen   +6 more
wiley   +1 more source

Biodiversity‐driven spatial conservation planning to delineate temporally stable regions

open access: yesConservation Biology, EarlyView.
Abstract The accelerating loss of biodiversity underscores the critical need for effective conservation strategies, particularly in the face of climate change and anthropogenic pressures. We devised a conservation planning framework that adopts a temporal stacking approach to species distribution models and landscape connectivity analyses. These models
Mattia Iannella   +5 more
wiley   +1 more source

‘There is more to life than HbA1c’: A comprehensive qualitative framework from the Hypo‐RESOLVE project evidencing the impacts of hypoglycaemia on the quality of life of adults living with type 1 or type 2 diabetes

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims To develop a comprehensive, in‐depth understanding of the impacts of hypoglycaemia on the quality of life of adults living with type 1 (T1D) or type 2 diabetes (T2D). Methods Thirty‐one adults with T1D or T2D who experienced hypoglycaemia participated in semi‐structured interviews.
Philip A. Powell   +12 more
wiley   +1 more source

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