Results 11 to 20 of about 6,486,745 (293)

Bilateral chemogenetic activation of intratelencephalic neurons in motor cortex reduces spontaneous locomotor activity in mice

open access: yesNeurobiology of Disease
Intratelencephalic neurons are a crucial class of cortical principal neurons that heavily innervate the striatum and cortical areas bilaterally. Their extensive cortico-cortical and cortico-striatal connectivity enables sensorimotor integration within ...
Mihai Atudorei   +5 more
doaj   +3 more sources

Effects of Cannabidiol on Locomotor Activity

open access: yesLife, 2022
Cannabidiol (CBD) is the second cannabinoid, in order of importance after Δ9-tetrahydrocannabinol (THC), from Cannabis sativa. Unlike THC, CBD does not cause psychotomimetic effects, and although these compounds have the same chemical formula, their ...
Fabrizio Calapai   +6 more
doaj   +2 more sources

Hypergravity and Aging in Drosophila melanogaster. 6. Spontaneous Locomotor Activity

open access: yesGerontology, 2009
The spontaneous locomotor activity (SLA) of Drosophila melanogaster flies kept at various gravity levels (1–5 g) was recorded in both longitudinal and cross-sectional experiments. No gravity level effect could be detected in the longitudinal one, probably because these flies were allowed (for technical reasons) to rest at 1 g for 15 % of their life. By
E, Le Bourg, F A, Lints
openaire   +3 more sources

Effect of famotidine in combination with antiepileptic drugs on locomotor activity in mice [PDF]

open access: yesCurrent Issues in Pharmacy and Medical Sciences, 2019
Histamine type 2 receptor antagonists are one of the most commonly used agents to treat peptic ulcer disease. Since patients with epilepsy may have many comorbidities, the aim of this study was to investigate the influence of one of the strongest second ...
Swiader Mariusz J.   +3 more
doaj   +2 more sources

Efffects of vigabatrin on spontaneous locomotor activity of rats

open access: yesNeuroscience Research Communications, 2003
AbstractEffects of vigibatrin (saline, 125, 250, or 500 mg/kg i.p.) on spontaneous locomotor activity in Wistar rats were investigated. There was a dose dependent decrease in amount of locomotion for doses up to 250 mg/kg. This decrease was measurable 2–4 hours after injection and still became more pronounced in the following hours.
Bouwman, B.M.   +3 more
openaire   +3 more sources

Spontaneous Locomotor Activity and Life Span [PDF]

open access: yesGerontology, 2009
The spontaneous locomotor activity and life span of approximately 600 individuals of both sexes and of three widely different genotypes of Drosophila melanogaster have been measured. Neither at the individual nor at the populational level could a significant correlation between spontaneous locomotor activity and life span be found.
F.A. Lints, E. Le Bourg, C.V. Lints
openaire   +1 more source

Influence of ketotifen and conventional antiepileptic drugs on the exploratory and spontaneous locomotor activity in mice [PDF]

open access: yes, 2021
Drug interactions are major problems in polytherapy, especially in epilepsy, and inappropriate drug selection may result in increased frequency of seizures.In this study, the influence of histamine type 1 (H1) receptor antagonist ketotifen and four ...
Swiader, Katarzyna   +2 more
core   +1 more source

The development of free-swimming in Xenopus laevis larvae [PDF]

open access: yes, 2013
In Xenopus laevis frog tadpoles, highly self-motive, free-swimming behaviour emerges at the onset of feeding. This is in contrast to the earlier post-hatched larval form, which is capable of escape swimming when stimulated, but normally lies dormant.
Scott, Nicholas W.
core   +2 more sources

Amplitude of the SCN clock enhanced by the behavioral activity rhythm. [PDF]

open access: yesPLoS ONE, 2012
Circadian rhythms are regulated by the suprachiasmatic nucleus (SCN), a small structure at the base of the hypothalamus. While light effects on the SCN are well established, little is known of behavioral effects.
Floor van Oosterhout   +5 more
doaj   +1 more source

Nitric oxide-mediated modulation of the murine locomotor network [PDF]

open access: yes, 2014
CD was supported by a BBSRC studentshipSpinal motor control networks are regulated by neuromodulatory systems to allow adaptability of movements. The present study aimed to elucidate the role of nitric oxide (NO) in the modulation of mammalian spinal ...
Miles, Gareth Brian   +5 more
core   +1 more source

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